SCHEMBL1355905

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1355941	0.92	EIF2AK4 (0.54)	EIF2AK4LMNAMAPTPIP4K2APTK2
	SCHEMBL1356733	0.85	CHRNA7 (0.47)	EIF2AK4LMNAMAPTPIP4K2ACRHR1
	SCHEMBL1356282	0.84	FLT3 (0.52)	EIF2AK4LMNAMAPTPIP4K2ACRHR1
	SCHEMBL1356855	0.84	EIF2AK4 (0.64)	EIF2AK4PTK2CDK4CCND1CCND2
	SCHEMBL1356000	0.83	AURKA (0.44)	EIF2AK4LMNAMAPTPIP4K2ACRHR1
	SCHEMBL1355282	0.82	KDR (0.46)	EIF2AK4LMNAMAPTPIP4K2APTK2
	SCHEMBL1355810	0.82	CDK4 (0.60)	CDK4CCND1CCND2CCND3TBK1
	SCHEMBL1355729	0.79	FGFR4 (0.50)	EIF2AK4MAPTCDK4EGFRBRD4
	SCHEMBL1356019	0.71	EIF2AK4 (0.61)	EIF2AK4MAPTPIP4K2APTK2CDK4
	SCHEMBL1356186	0.71	EIF2AK4 (0.67)	EIF2AK4PTK2CDK4CCND1CCND2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.