SCHEMBL1356016

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1353786	0.89	EIF2AK4 (0.62)	GSK3BGSK3AAURKACHEK1NTRK2
	SCHEMBL1355529	0.85	EIF2AK4 (0.53)	GSK3BAURKAPTK2EIF2AK4CDK4
	SCHEMBL13764025	0.84	GSK3B (0.76)	GSK3BGSK3AAURKACHEK1NTRK2
	SCHEMBL1356046	0.84	FLT3 (0.54)	GSK3BAURKAEIF2AK4CDK4USP2
	SCHEMBL1356097	0.82	MAPT (0.52)	AURKANTRK2PTK2EIF2AK4CDK4
	SCHEMBL1355283	0.82	EIF2AK4 (0.52)	AURKAPTK2EIF2AK4CDK4USP2
	SCHEMBL1355910	0.82	FGFR4 (0.50)	GSK3BAURKAEIF2AK4CDK4USP2
	SCHEMBL1353652	0.82	CDK4 (0.54)	AURKANTRK2PTK2EIF2AK4CDK4
	SCHEMBL1355878	0.82	EIF2AK4 (0.49)	AURKAPTK2EIF2AK4CDK4USP2
	SCHEMBL1355852	0.80	FGFR4 (0.63)	AURKAEIF2AK4CDK4JAK2FGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.