Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10456965 | 0.84 | TSHR (0.73) | TSHRHSD17B10CYP2A6HRH3LOXL2 | |
| SCHEMBL2041798 | 0.84 | TSHR (0.73) | TSHRHSD17B10CYP2A6HRH3LOXL2 | |
| SCHEMBL8377264 | 0.83 | TSHR (0.51) | TSHRHSD17B10CYP2A6KDM1ALTB4R2 | |
| SCHEMBL9317548 | 0.83 | TSHR (0.71) | TSHRHSD17B10CYP2A6HRH3LOXL2 | |
| SCHEMBL8379783 | 0.83 | TSHR (0.71) | TSHRHSD17B10CYP2A6HRH3LOXL2 | |
| SCHEMBL18322222 | 0.82 | TSHR (0.52) | TSHRCYP2A6MAOAMAOBCYP11B2 | |
| SCHEMBL885099 | 0.82 | CYP2A6 (0.67) | TSHRHSD17B10CYP2A6MAOAMAOB | |
| SCHEMBL30451858 | 0.82 | TSHR (0.52) | TSHRCYP2A6MAOAMAOBCYP11B2 | |
| SCHEMBL25188141 | 0.80 | CYP2A6 (0.70) | TSHRHSD17B10CYP2A6HRH3LOXL2 | |
| SCHEMBL6033048 | 0.79 | HSD17B10 (0.77) | TSHRHSD17B10CYP2A6LTB4R2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120273724-A1 | COMPOUNDS FOR A LIQUID-CRYSTALLINE MEDIUM, AND USE FOR HIGH-FREQUENCY COMPONENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120273724-A1 | COMPOUNDS FOR A LIQUID-CRYSTALLINE MEDIUM, AND USE FOR HIGH-FREQUENCY COMPONENTS | CCNA1, C1S, CCNT1 | TSHR 4348/4885HSD17B10 3268/4885CYP2A6 1503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.