SCHEMBL30451858

SCHEMBL30451858

N#Cc1ccc(-c2ccc(-c3ccc(C#N)cc3)c3ccccc23)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.52
MMP3 P08254 1/20 0.48
TNKS O95271 1/20 0.46
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
CYP11B2 P19099 2/20 0.44
KIF11 P52732 2/20 0.43
PDK2 Q15119 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ATM Q13315 1/20 0.42
TDO2 P48775 1/20 0.42
CA2 P00918 3/20 0.42
CA1 P00915 2/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP2A6 P11509 1/20 0.42
CA12 O43570 1/20 0.42
CA3 P07451 1/20 0.42
CA6 P23280 1/20 0.42
CA9 Q16790 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18322222 1.00 TSHR (0.52) TSHRMMP3TNKSMAOAMAOB
SCHEMBL23624495 0.90 MAOA (0.50) TSHRMMP3TNKSMAOAMAOB
SCHEMBL22049794 0.90 ALDH1A1 (0.61) TSHRMMP3TNKSCYP11B2KIF11
SCHEMBL23624435 0.90 MAOB (0.50) TSHRMMP3TNKSMAOAMAOB
SCHEMBL13170996 0.88 TNKS (0.43) TSHRMMP3TNKSMAOAMAOB
SCHEMBL23624359 0.88 CYP1A2 (0.48) TSHRMMP3TNKSMAOAMAOB
SCHEMBL20733779 0.88 CYP1A2 (0.48) TSHRMMP3TNKSCYP11B2KIF11
SCHEMBL21313428 0.88 TSHR (0.41) TSHRMMP3TNKSMAOAMAOB
SCHEMBL30708993 0.88 MAOA (0.48) TSHRMMP3TNKSMAOAMAOB
SCHEMBL29847362 0.88 TSHR (0.41) TSHRMMP3TNKSMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116162253-A Cu (I) -MOF coordination compound SUST-WZ3 for realizing ultra-long near infrared room temperature phosphorescence and preparation method thereof 陕西科技大学 2023-05-26 CN claimed
CN-116162253-A Cu (I) -MOF coordination compound SUST-WZ3 for realizing ultra-long near infrared room temperature phosphorescence and preparation method thereof 陕西科技大学 2023-05-26 CN disclosed