Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 12/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30385581 | 0.82 | CYP11B2 (0.77) | CYP11B2CYP19A1CYP11B1EGLN1BACE1 | |
| SCHEMBL1041611 | 0.82 | CYP11B2 (0.77) | CYP11B2CYP19A1CYP11B1EGLN1BACE1 | |
| SCHEMBL16200646 | 0.78 | CYP11B2 (0.80) | CYP11B2CYP19A1CYP11B1EGLN1 | |
| SCHEMBL1036346 | 0.77 | CYP11B2 (0.66) | CYP11B2CYP19A1CYP11B1AR | |
| SCHEMBL31326542 | 0.77 | CYP11B2 (0.85) | CYP11B2CYP19A1CYP11B1AR | |
| SCHEMBL1040554 | 0.77 | CYP11B2 (0.85) | CYP11B2CYP19A1CYP11B1AR | |
| SCHEMBL13563929 | 0.76 | CYP11B2 (0.83) | CYP11B2CYP19A1CYP11B1AR | |
| SCHEMBL30385587 | 0.75 | CYP11B2 (0.75) | CYP11B2CYP19A1CYP11B1EGLN1BACE1 | |
| SCHEMBL1040977 | 0.75 | CYP11B2 (0.75) | CYP11B2CYP19A1CYP11B1EGLN1BACE1 | |
| SCHEMBL1040490 | 0.75 | CYP11B2 (1.00) | CYP11B2CYP19A1CYP11B1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120277215-A1 | Organic Compounds | RECORDATI AG (CH) | 2012-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277215-A1 | Organic Compounds | CYP19A1, CYP17A1, HSD17B11 | CYP11B2 14/4885CYP19A1 1/4885CYP11B1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.