Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 5/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13565258 | 0.86 | CNR2 (0.47) | CNR2EPHX1ARCNR1GSTO1 | |
| SCHEMBL13565214 | 0.84 | GRIA1 (0.46) | CNR2ARCNR1FFAR4 | |
| SCHEMBL10115341 | 0.84 | GSTO1 (0.46) | GSTO1MAPT | |
| SCHEMBL11935657 | 0.84 | CNR2 (0.49) | CNR2EPHX1ARCNR1 | |
| SCHEMBL13565955 | 0.83 | CNR2 (0.44) | CNR2CNR1POLBL3MBTL1 | |
| SCHEMBL11935708 | 0.80 | AR (0.42) | CNR2ARPOLBABL1 | |
| SCHEMBL11935312 | 0.79 | MAPT (0.43) | CNR2EPHX1POLBMAPTL3MBTL1 | |
| SCHEMBL13565792 | 0.79 | EPHX1 (0.41) | CNR2EPHX1POLBMAPTFFAR4 | |
| SCHEMBL13565161 | 0.78 | CNR2 (0.40) | CNR2EPHX1CNR1POLBMAPT | |
| SCHEMBL13564900 | 0.77 | PTGS1 (0.41) | CNR2EPHX1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |