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Sugi Predict / Targets / GSTO1

GSTO1

Glutathione S-transferase omega-1 · P78417 · GSTO1 on Sugi Atlas →

15,923 patent compounds predicted against GSTO1, 10,807 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL453503 SCHEMBL453503 0.63 7/20
SCHEMBL1746506 SCHEMBL1746506 0.54 7/20
SCHEMBL1008822 SCHEMBL1008822 0.45 6/20
SCHEMBL449608 SCHEMBL449608 0.58 5/20
SCHEMBL1747119 SCHEMBL1747119 0.49 5/20
SCHEMBL1744722 SCHEMBL1744722 0.49 5/20
SCHEMBL38611 SCHEMBL38611 0.43 4/20
SCHEMBL1745189 SCHEMBL1745189 0.54 3/20
SCHEMBL1747118 SCHEMBL1747118 0.52 3/20
SCHEMBL1744789 SCHEMBL1744789 0.48 3/20
SCHEMBL1745545 SCHEMBL1745545 0.48 3/20
SCHEMBL917175 SCHEMBL917175 0.47 3/20
SCHEMBL1746924 SCHEMBL1746924 0.47 3/20
SCHEMBL917176 SCHEMBL917176 0.44 3/20
SCHEMBL37919 SCHEMBL37919 0.43 3/20
SCHEMBL1723444 SCHEMBL1723444 0.36 3/20
(+)-Alpha-Tocopheryl Succinate (+)-Alpha-Tocopheryl Succinate (SCHEMBL134422) 1.00 2/20
SCHEMBL628454 SCHEMBL628454 1.00 2/20
SCHEMBL278119 SCHEMBL278119 0.89 2/20
SCHEMBL984154 SCHEMBL984154 0.80 2/20

Clinical trials — most relevant to GSTO1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Evaluation of The Effect of Rutin and Vitamin C on the Oxidative Stress in Hemodialysis Patients PHASE3UNKNOWN
Phase IIIB Extension Clinical Trial of Efficacy and Safety of GST-HG141 (Nairevir) Combined With NAs in Chronic Hepatitis B PHASE3NOT_YET_RECRUITING
Paracetamol Toxicity in Septic Patients PHASE3SUSPENDED
To Evaluate the Efficacy, Safety and Population Pharmacokinetics of GST-HG141 in Patients With Chronic Hepatitis B (CHB) Who Have an Inadequate Response to Antiviral Drug Treatment PHASE3RECRUITING
Prevent Cardiac Surgery Associated AKI Trial PHASE2RECRUITING
Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled LPS PHASE1/PHASE2COMPLETED
Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy PHASE2RECRUITING
Sulforaphane in a New Jersey (NJ) Population of Individuals With Autism PHASE2ACTIVE_NOT_RECRUITING
Broccoli Sprout Extracts Trial to See if NRF2 is Enhanced by Sulforaphane Treatment in Patients With COPD PHASE2COMPLETED
DHA For The Treatment of Pediatric Concussion Related to Sports Injury PHASE1COMPLETED
Tolerability of Enteral NAC in Infants PHASE1NOT_YET_RECRUITING
Pharmacokinetics, Metabolism and Analgesic Effects of Flupirtine PHASE1COMPLETED
Broccoli and Vascular Health Study nanCOMPLETED
The Conversion of ENcapsulated GlucorAphanin, Gut Microbiota Phylogeny and gEnotype Study (ENGAGE) nanCOMPLETED
Mechanisms of Response to Diesel Exhaust in Subjects With Asthma nanWITHDRAWN
Usefulness of Alpha-GST in Liver Transplantation nanUNKNOWN
Effect of Sulfur Amino Acid Depletion and Acetaminophen on Plasma Glutatione nanCOMPLETED
Studying Urine and Blood Samples in Women With Newly Diagnosed Breast Cancer nanCOMPLETED
Developing Treatment, Treatment Validation and Treatment Scope in the Setting of an Autism Clinical Trial nanACTIVE_NOT_RECRUITING
Pathogenic Insights and Search for Biomarkers in RFC1-ataxia/CANVAS nanRECRUITING
Reactive Oxygen Species Following Aortic Valve Replacement nanCOMPLETED
Impact Of Choline in Patients With NAFLD nanUNKNOWN
Physical Fitness Effect on the Different Oxidative Stress Measurements nanCOMPLETED
Personalizing Preterm Neonatal Transfusions With Fetal Hemoglobin-Enriched Cord Blood nanNOT_YET_RECRUITING
Dietary and Genetic Factors in Asthma & Chronic Bronchitis in a Cohort of Chinese Singaporeans nanCOMPLETED
Cancer and Hearing Loss Related in Children nanCOMPLETED
Genetic Polymorphisms in UGT1A6 and UGT2B7 in Asian Population: Association With Lung Cancer Phenotype nanUNKNOWN
Factors in Childhood Lung Susceptibility to Pollution nanCOMPLETED
Dietary Effects of Sulfur Amino Acids nanCOMPLETED
Pharmacokinetics and Safety of GST-HG171 Tablets in Subjects With Impaired and Normal Renal Function nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a GSTO1 binder may also engage these)

ProteinNameSimilarity
Q9Z339 — 0.986 Q9Z339 →
Q9N1F5 — 0.986 Q9N1F5 →
Q6AXV9 — 0.977 Q6AXV9 →
O09131 — 0.976 O09131 →
P20135 — 0.971 P20135 →
Q8K2Q2 — 0.967 Q8K2Q2 →
Q9D4P7 — 0.964 Q9D4P7 →
Q4V8E6 — 0.962 Q4V8E6 →
P30568 — 0.961 P30568 →
A0A1W2PR19 — 0.958 A0A1W2PR19 →
Q64471 — 0.957 Q64471 →
P30713 — 0.957 P30713 →
Q9H4Y5 — 0.955 Q9H4Y5 →
P0CG29 — 0.955 P0CG29 →
Q61133 — 0.955 Q61133 →
Q01579 — 0.954 Q01579 →
P0CG30 — 0.953 P0CG30 →
Q5HYI7 — 0.952 Q5HYI7 →
P30711 — 0.951 P30711 →
Q8TB36 — 0.950 Q8TB36 →
O88741 — 0.950 O88741 →
Q2L969 — 0.950 Q2L969 →
P28342 — 0.949 P28342 →
Q9D1M4 — 0.948 Q9D1M4 →
Q2NL00 — 0.948 Q2NL00 →
P24473 — 0.947 P24473 →
Q9DCM2 — 0.947 Q9DCM2 →
A6QQZ0 — 0.946 A6QQZ0 →
O88441 — 0.946 O88441 →
Q94E75 — 0.946 Q94E75 →