Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.39 |
| ▸ | CCNK | O75909 | 4/20 | 0.38 |
| ▸ | CDK9 | P50750 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | AQP1 | P29972 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090500 | 1.00 | PTPN2 (0.41) | PTPN2PTPN1MAPTMEN1KMT2A | |
| SCHEMBL13565678 | 0.87 | MEN1 (0.44) | PTPN2PTPN1MAPTMEN1KMT2A | |
| SCHEMBL13203777 | 0.83 | RAB9A (0.47) | MAPTMEN1KMT2ANPY5RALDH1A1 | |
| SCHEMBL10133352 | 0.83 | RAB9A (0.47) | MAPTMEN1KMT2ANPY5RALDH1A1 | |
| SCHEMBL13438697 | 0.80 | CCNK (0.51) | PTPN2PTPN1MAPTMEN1KMT2A | |
| SCHEMBL11934826 | 0.80 | CCNK (0.51) | PTPN2PTPN1MAPTMEN1KMT2A | |
| SCHEMBL13564740 | 0.78 | NPC1 (0.42) | NPY5RCCNKCDK9ALDH1A1 | |
| SCHEMBL17089947 | 0.78 | NPC1 (0.42) | NPY5RCCNKCDK9ALDH1A1 | |
| SCHEMBL13565525 | 0.75 | NPY5R (0.54) | PTPN2PTPN1NPY5R | |
| SCHEMBL11935361 | 0.75 | NPC1 (0.47) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |