Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 5/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 2/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113817 | 0.82 | SMN1; SMN2 (0.45) | CA2CA12CA1CA4CA9 | |
| SCHEMBL13565493 | 0.82 | CA2 (0.49) | CA2CA12CA1CA4CA9 | |
| SCHEMBL21379748 | 0.82 | HPGD (0.63) | CA2CA12CA1CA4CA9 | |
| SCHEMBL13105490 | 0.81 | GRIA1 (0.45) | GRIA1SLC2A1 | |
| SCHEMBL23740252 | 0.78 | SLC2A1 (0.55) | CA2CA12CA9SLC2A1FOLH1 | |
| SCHEMBL13105494 | 0.77 | NPY5R (0.67) | CA2GRIA1CA12CA1CA4 | |
| Hydrochloric Acid SCHEMBL17260141 | 0.76 | SLC2A1 (0.54) | SLC2A1HPGDCYP1A2CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL17260137 | 0.76 | SLC2A1 (0.54) | SLC2A1HPGDCYP1A2CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL17260156 | 0.76 | SLC2A1 (0.54) | SLC2A1HPGDCYP1A2CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL17260133 | 0.76 | SLC2A1 (0.54) | SLC2A1HPGDCYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139518-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-09-22 | — | — | US | disclosed |
| US-8299265-B2 | Amine derivatives having NPY Y5 receptor antagonistic activity and the uses thereof | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |