Trolamine

Trolamine

SCHEMBL135684

CC(=O)O.OCCN(CCO)CCO

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Trolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A known ✓ P08913 1/20 0.35
FFAR3 O14843 2/20 0.44
LCK P06239 1/20 0.44
FYN P06241 1/20 0.44
ALOX15 P16050 3/20 0.42
MAPT P10636 2/20 0.42
KDM4E B2RXH2 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 3/20 0.36
EYA2 O00167 1/20 0.36
APP P05067 1/20 0.36
ACE P12821 1/20 0.36
TRPA1 O75762 1/20 0.35
LMNA P02545 3/20 0.35
TSHR P16473 3/20 0.35
CYP2C19 P33261 2/20 0.35
CHRM2 P08172 1/20 0.35
DRD1 P21728 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL28327104 1.00 FFAR3 (0.44) FFAR3LCKFYNALOX15MAPT
Trolamine SCHEMBL28634962 1.00 FFAR3 (0.44) FFAR3LCKFYNALOX15MAPT
Trolamine SCHEMBL29400146 1.00 FFAR3 (0.44) FFAR3LCKFYNALOX15MAPT
Trolamine SCHEMBL238201 1.00 FFAR3 (0.44) FFAR3LCKFYNALOX15MAPT
Trolamine SCHEMBL11411163 0.97 FFAR3 (0.41) FFAR3LCKFYNALOX15MAPT
Trolamine SCHEMBL27977489 0.97 FFAR3 (0.41) FFAR3LCKFYNALOX15MAPT
Trolamine SCHEMBL3631034 0.97 FFAR3 (0.41) FFAR3LCKFYNALOX15MAPT
Trolamine SCHEMBL30722438 0.97 FFAR3 (0.41) FFAR3LCKFYNALOX15MAPT
Trolamine SCHEMBL18317908 0.94 ALOX15 (0.39) FFAR3LCKFYNALOX15MAPT
Trolamine SCHEMBL28456833 0.90 KDM4E (0.44) ALOX15MAPTKDM4ESMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2719 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058251-A Calcareous rebound inhibitor for sprayed concrete and preparation method and application thereof 江苏苏博特新材料股份有限公司 2025-05-30 CN claimed
CN-120004525-A Magnesia rebound inhibitor for sprayed concrete and preparation method and application thereof 江苏苏博特新材料股份有限公司 2025-05-16 CN claimed
CN-115923368-B Water-soluble polyvinyl alcohol patterned film 孙琇芳 2025-03-21 CN claimed
US-20240138403-A1 Synergistic Combinations for Reducing Volatility of Auxin Herbicides ETHOX CHEMICALS, LLC 2024-05-02 US claimed
CN-117542726-A Semiconductor device cleaning method and semiconductor device 粤芯半导体技术股份有限公司 2024-02-09 CN claimed
US-11858848-B2 Regulating cementitious material for promoting hydration of Portland cement BEIJING UNIVERSITY OF TECHNOLOGY (CN) 2024-01-02 US claimed
CN-117192046-A Method for monitoring effective etching of cleaning reagent 粤芯半导体技术股份有限公司 2023-12-08 CN claimed
EP-4203966-A1 FORMULATIONS FOR REDUCING HAIR LOSS AND/OR INCREASING HAIR REGROWTH Triple Hair Inc. (CA) 2023-07-05 EP claimed
CN-115923368-A Water-soluble polyvinyl alcohol pattern film 孙琇芳 2023-04-07 CN claimed
CN-115716922-A Lignin demethylation method based on low-cost proton type ionic liquid 北京理工大学 2023-02-28 CN claimed
EP-0347663-A1 Method for sealing-in anodised films on aluminium and aluminium alloys Henkel Kommanditgesellschaft auf Aktien (DE) 1989-12-27 EP claimed
EP-0058959-B1 METHOD FOR PREPARING LOW-TURBIDITY STANDARD OR REFERENCE SERA Roche Diagnostics GmbH (DE) 1988-12-21 EP claimed
US-4716119-A REDUCTION OF TURBIDITY IN RECONSTITUTED LYOPHILIZED SAMPLE BOEHRINGER MANNHEIM GMBH (DE) 1987-12-29 US claimed
US-4465614-A Alkanolaminium carboxylate solvents for selective SO2 absorption TRENTHAM CORPORATION (US) 1984-08-14 US claimed
EP-0036106-B1 SYNERGISTIC MIXTURES OF PHOSPHINOTHRICINE HOECHST AKTIENGESELLSCHAFT (DE) 1983-09-28 EP claimed
US-4387037-A REDUCING DEGRADATION OF A TRIALKYL PHOSPHATE SOLVENT USING A ALKANOLAMINIUM CARBOXYLATE, OR ALKALI METAL(OR AMMONIUM SALT) OF CARBOXYLIC OR BENZOIC ACID TRENTHAM CORPORATION (US) 1983-06-07 US claimed
US-4363791-A Alkanolaminium carboxylate solvents for selective SO2 absorption TRENTHAM CORPORATION (US) 1982-12-14 US claimed
US-4320101-A TRIALKYL PHOSPHATE SOLVENT TRENTHAM CORPORATION (US) 1982-03-16 US claimed
US-4016115-A Unsaturated polyester resin composition containing titanium dioxide TOYO BOSEKI KABUSHIKI KAISHA (JA) 1977-04-05 US claimed
US-4001142-A DYES, BUFFERS, ORGANIC ACIDS, OXYGEN, NITROGEN, CARBON DIOXIDE, BICARBONATE ANION WARNER-LAMBERT COMPANY (US) 1977-01-04 US claimed