Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.42 |
| ▸ | CA1 | P00915 | 7/20 | 0.42 |
| ▸ | CA2 | P00918 | 7/20 | 0.42 |
| ▸ | CA3 | P07451 | 7/20 | 0.42 |
| ▸ | CA6 | P23280 | 7/20 | 0.42 |
| ▸ | CA7 | P43166 | 7/20 | 0.42 |
| ▸ | CA5A | P35218 | 6/20 | 0.42 |
| ▸ | CA9 | Q16790 | 6/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 5/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13568846 | 0.88 | CA12 (0.44) | CA12CA1CA2CA3CA6 | |
| SCHEMBL13568723 | 0.88 | CA12 (0.44) | CA12CA1CA2CA3CA6 | |
| SCHEMBL13568818 | 0.87 | CA12 (0.53) | CA12CA1CA2CA3CA6 | |
| SCHEMBL13568805 | 0.85 | CA1 (0.46) | CA12CA1CA2CA3CA6 | |
| SCHEMBL13568775 | 0.84 | ROCK2 (0.47) | CA12CA1CA2CA3CA6 | |
| SCHEMBL13568850 | 0.83 | CA12 (0.47) | CA12CA1CA2CA3CA6 | |
| SCHEMBL13568843 | 0.83 | CA12 (0.42) | CA12CA1CA2CA3CA6 | |
| SCHEMBL13568792 | 0.83 | CA12 (0.47) | CA12CA1CA2CA3CA6 | |
| SCHEMBL13568826 | 0.83 | MEN1 (0.42) | CA12CA1CA2CA3CA6 | |
| SCHEMBL13568713 | 0.83 | CA12 (0.41) | CA12CA1CA2CA3CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2138482-A1 | BICYCLIC HETEROCYCLIC COMPOUND | Astellas Pharma Inc. (JP) | 2009-12-30 | — | — | EP | disclosed |