Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13569336 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9ALMNACTSK | |
| SCHEMBL3226529 | 0.90 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL13569333 | 0.90 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL15317909 | 0.90 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL1554809 | 0.87 | CA1 (0.58) | SMN1; SMN2NPC1RAB9ALMNACTSK | |
| SCHEMBL16553626 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9ALMNAHTT | |
| SCHEMBL13569327 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL13569340 | 0.84 | LMNA (0.48) | SMN1; SMN2NPC1RAB9ALMNACTSK | |
| SCHEMBL13569337 | 0.84 | LMNA (0.48) | SMN1; SMN2NPC1RAB9ALMNACTSK | |
| SCHEMBL6216286 | 0.80 | LMNA (0.58) | SMN1; SMN2NPC1RAB9ALMNACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632972-B2 | Reacting an acid and an amine; apoptosis; carbamate, and N-phenethyl-2-phenylacetamide | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLIONIS (US) | 2009-12-15 | — | — | US | disclosed |