Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 6/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL520958 | 0.77 | DRD4 (0.47) | DRD4TLR9TLR8TLR7DRD2 | |
| SCHEMBL21355672 | 0.76 | NOS3 (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3436370 | 0.75 | DRD4 (0.59) | DRD4DRD2DRD3 | |
| SCHEMBL3436615 | 0.74 | OPRL1 (0.50) | DRD4SCN9ACCNT1CDK9 | |
| SCHEMBL3447668 | 0.73 | KDM4E (0.50) | JAK2JAK3 | |
| SCHEMBL3436049 | 0.73 | CYP2C19 (0.44) | DRD4SCN9A | |
| SCHEMBL31128333 | 0.73 | NOS3 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13548519 | 0.73 | DRD4 (0.42) | DRD4TLR9TLR8TLR7DRD2 | |
| Hydrochloric Acid SCHEMBL2078695 | 0.72 | CYP2C19 (0.43) | DRD4SCN9A | |
| SCHEMBL3436234 | 0.72 | CCNT1 (0.44) | DRD4SCN9ACCNT1CDK9HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158431-A2 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | IRM LLC (BM) | 2009-12-30 | — | — | WO | disclosed |