Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1I | Q9P0X4 | 10/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.51 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4274501 | 0.83 | CACNA1I (0.67) | CACNA1IKCNH2CACNA1HCACNA1GCCR2 | |
| SCHEMBL13569787 | 0.82 | KCNH2 (0.51) | CACNA1IKCNH2CCR2USP30CXCR3 | |
| SCHEMBL20056294 | 0.80 | KCNH2 (0.50) | CACNA1IKCNH2CACNA1HCACNA1GCCR2 | |
| SCHEMBL13569759 | 0.78 | KCNH2 (0.56) | CACNA1IKCNH2CCR2CXCR3MCHR1 | |
| SCHEMBL13569792 | 0.78 | KCNH2 (0.57) | CACNA1IKCNH2CACNA1HCCR2KMT2A | |
| SCHEMBL13569697 | 0.78 | KCNH2 (0.45) | CACNA1IKCNH2CACNA1HCACNA1GCCR2 | |
| SCHEMBL13569803 | 0.77 | CACNA1I (0.67) | CACNA1IKCNH2CACNA1HCACNA1GCCR2 | |
| SCHEMBL13569689 | 0.76 | KCNH2 (0.49) | CACNA1IKCNH2CACNA1HCACNA1GCCR2 | |
| SCHEMBL13569688 | 0.75 | KCNH2 (0.49) | CACNA1IKCNH2CACNA1HCACNA1GCCR2 | |
| SCHEMBL13569764 | 0.73 | KCNH2 (0.65) | CACNA1IKCNH2CACNA1HCACNA1GCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146540-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS LTD (CA) | 2009-12-10 | — | — | WO | disclosed |