Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.67 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.67 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12608100 | 0.90 | CYP2E1 (0.56) | CYP2A6CYP2E1CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL12608111 | 0.86 | CYP2A6 (0.56) | CYP2A6CYP2E1CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL4135591 | 0.86 | CYP2A6 (0.56) | CYP2A6CYP2E1CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL7423578 | 0.86 | CYP3A4 (0.56) | CYP2A6CYP2E1CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL4135586 | 0.86 | CYP2C9 (0.56) | CYP2A6CYP2E1CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL26387047 | 0.86 | CYP2E1 (0.56) | CYP2A6CYP2E1CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL30613331 | 0.86 | CYP2A6 (0.56) | CYP2A6CYP2E1CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL30722437 | 0.83 | TOP1 (0.61) | CYP2A6CYP2E1CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL31418324 | 0.83 | CYP3A4 (0.53) | CYP2A6CYP2E1CYP3A4CYP2C9CYP2B6 | |
| SCHEMBL4338418 | 0.83 | KCNH2 (0.58) | CYP2A6CYP2E1CYP3A4CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9518964-B2 | Method for identifying electrophiles and nucleophiles in a sample | EICHEN YOAV (IL) | 2016-12-13 | — | — | US | disclosed |
| US-9518964-B2 | Method for identifying electrophiles and nucleophiles in a sample | EICHEN YOAV (IL) | 2016-12-13 | — | — | US | disclosed |
| US-9518964-B2 | Method for identifying electrophiles and nucleophiles in a sample | EICHEN YOAV (IL) | 2016-12-13 | — | — | US | disclosed |
| US-20110281742-A1 | METHOD FOR IDENTIFYING ELECTROPHILES AND NUCLEOPHILES IN A SAMPLE | EICHEN YOAV (IL) | 2011-11-17 | — | — | US | disclosed |
| US-20110281742-A1 | METHOD FOR IDENTIFYING ELECTROPHILES AND NUCLEOPHILES IN A SAMPLE | EICHEN YOAV (IL) | 2011-11-17 | — | — | US | disclosed |
| US-20110281742-A1 | METHOD FOR IDENTIFYING ELECTROPHILES AND NUCLEOPHILES IN A SAMPLE | EICHEN YOAV (IL) | 2011-11-17 | — | — | US | disclosed |
| US-20090258430-A1 | Method for identifying electrophiles and nucleophiles in a sample | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2009-10-15 | — | — | US | disclosed |
| US-20090258430-A1 | Method for identifying electrophiles and nucleophiles in a sample | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2009-10-15 | — | — | US | disclosed |
| US-20090258430-A1 | Method for identifying electrophiles and nucleophiles in a sample | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2009-10-15 | — | — | US | disclosed |
| EP-2085766-A2 | Method for identifying electrophiles and nucleophiles in a sample | Technion Research and Development Foundation, Ltd. (IL) | 2009-08-05 | — | — | EP | disclosed |
| EP-2085766-A2 | Method for identifying electrophiles and nucleophiles in a sample | Technion Research and Development Foundation, Ltd. (IL) | 2009-08-05 | — | — | EP | disclosed |