Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 3/20 | 0.52 |
| ▸ | DPP4 | P27487 | 8/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.43 |
| ▸ | CDK2 | P24941 | 4/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21696738 | 1.00 | VHL (0.52) | VHLDPP4CCNE1CDK2GSK3B | |
| SCHEMBL15126220 | 0.89 | VHL (0.53) | VHLCCNE1CDK2GSK3BPREP | |
| SCHEMBL21696618 | 0.86 | VHL (0.53) | VHLDPP4CCNE1CDK2GSK3B | |
| SCHEMBL21696556 | 0.84 | CCNE1 (0.54) | VHLCCNE1CDK2GSK3B | |
| SCHEMBL15112607 | 0.84 | VHL (0.55) | VHLCCNE1CDK2GSK3B | |
| SCHEMBL21696439 | 0.84 | CCNE1 (0.54) | VHLCCNE1CDK2GSK3B | |
| SCHEMBL21696674 | 0.81 | VHL (0.50) | VHLCCNE1CDK2GSK3B | |
| SCHEMBL16277194 | 0.80 | VHL (0.76) | VHLCCNE1CDK2GSK3B | |
| SCHEMBL15125912 | 0.80 | VHL (0.76) | VHLCCNE1CDK2GSK3B | |
| SCHEMBL21696706 | 0.79 | CCNE1 (0.54) | VHLCCNE1CDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519506-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-11-07 | — | — | EP | claimed |