Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.62 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MMP1 | P03956 | 3/20 | 0.61 |
| ▸ | MMP3 | P08254 | 3/20 | 0.61 |
| ▸ | MMP7 | P09237 | 3/20 | 0.61 |
| ▸ | MMP13 | P45452 | 2/20 | 0.61 |
| ▸ | MMP9 | P14780 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13571490 | 0.90 | USP2 (0.67) | FKBP1AUSP2GAAHCRTR1HCRTR2 | |
| SCHEMBL13571191 | 0.89 | FKBP1A (0.77) | FKBP1ATDP1RAB9AMMP9 | |
| SCHEMBL13570758 | 0.85 | FKBP1A (0.69) | FKBP1ATDP1RAB9A | |
| SCHEMBL13571106 | 0.85 | FKBP1A (0.69) | FKBP1ATDP1RAB9A | |
| SCHEMBL13570871 | 0.85 | TDP1 (0.69) | FKBP1AUSP2GAATDP1RAB9A | |
| SCHEMBL15244866 | 0.84 | FKBP1A (0.67) | FKBP1ATDP1 | |
| SCHEMBL13570706 | 0.83 | FKBP1A (0.66) | FKBP1ATDP1HCRTR1HCRTR2 | |
| SCHEMBL13570707 | 0.83 | FKBP1A (0.66) | FKBP1ATDP1HCRTR1HCRTR2 | |
| SCHEMBL13570817 | 0.81 | ATM (0.77) | FKBP1ATDP1RAB9A | |
| SCHEMBL13571310 | 0.81 | TDP1 (0.61) | FKBP1AUSP2GAATDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012152983-A1 | PHENYL- SULFONYL DERIVATIVES AS MEDIATORS OF TRPA1 RECEPTOR ACTIVITY FOR THE TREATMENT OF PAIN | ORION CORPORATION (FI) | 2012-11-15 | — | — | WO | claimed |
| EP-2520566-A1 | New Pharmaceutical Compounds | Orion Corporation (FI) | 2012-11-07 | — | — | EP | claimed |
| WO-2012152983-A1 | PHENYL- SULFONYL DERIVATIVES AS MEDIATORS OF TRPA1 RECEPTOR ACTIVITY FOR THE TREATMENT OF PAIN | ORION CORPORATION (FI) | 2012-11-15 | — | — | WO | disclosed |
| EP-2520566-A1 | New Pharmaceutical Compounds | Orion Corporation (FI) | 2012-11-07 | — | — | EP | disclosed |