Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 6/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13570536 | 1.00 | FKBP1A (0.62) | FKBP1ATDP1ATMMAPTL3MBTL1 | |
| SCHEMBL13571273 | 0.91 | TSHR (0.65) | FKBP1ATDP1ATMMAPTL3MBTL1 | |
| SCHEMBL13571274 | 0.91 | TSHR (0.65) | FKBP1ATDP1ATMMAPTL3MBTL1 | |
| SCHEMBL13571191 | 0.88 | FKBP1A (0.77) | FKBP1ATDP1ATML3MBTL1POLB | |
| SCHEMBL13571408 | 0.86 | FKBP1A (0.64) | FKBP1ATDP1ATMMAPTL3MBTL1 | |
| SCHEMBL13571407 | 0.86 | FKBP1A (0.64) | FKBP1ATDP1ATMMAPTL3MBTL1 | |
| SCHEMBL13570949 | 0.84 | FKBP1A (0.60) | FKBP1ATDP1ATML3MBTL1POLB | |
| SCHEMBL13570951 | 0.84 | FKBP1A (0.60) | FKBP1ATDP1ATML3MBTL1POLB | |
| SCHEMBL894013 | 0.81 | ATM (0.67) | FKBP1ATDP1ATMMAPTL3MBTL1 | |
| SCHEMBL13570491 | 0.81 | FKBP1A (0.61) | FKBP1ATDP1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012152983-A1 | PHENYL- SULFONYL DERIVATIVES AS MEDIATORS OF TRPA1 RECEPTOR ACTIVITY FOR THE TREATMENT OF PAIN | ORION CORPORATION (FI) | 2012-11-15 | — | — | WO | claimed |
| EP-2520566-A1 | New Pharmaceutical Compounds | Orion Corporation (FI) | 2012-11-07 | — | — | EP | claimed |
| WO-2012152983-A1 | PHENYL- SULFONYL DERIVATIVES AS MEDIATORS OF TRPA1 RECEPTOR ACTIVITY FOR THE TREATMENT OF PAIN | ORION CORPORATION (FI) | 2012-11-15 | — | — | WO | disclosed |
| EP-2520566-A1 | New Pharmaceutical Compounds | Orion Corporation (FI) | 2012-11-07 | — | — | EP | disclosed |