Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.59 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13571358 | 0.92 | ATM (0.74) | ATMTSHRFKBP1AMAPTTDP1 | |
| SCHEMBL13571316 | 0.91 | ATM (0.64) | ATMTRPA1TSHRFKBP1AMAPT | |
| SCHEMBL13570707 | 0.91 | FKBP1A (0.66) | ATMTRPA1FKBP1ABRD4TDP1 | |
| SCHEMBL13570706 | 0.91 | FKBP1A (0.66) | ATMTRPA1FKBP1ABRD4TDP1 | |
| SCHEMBL13571127 | 0.88 | TSHR (0.64) | ATMTRPA1TSHRFKBP1AMAPT | |
| SCHEMBL893040 | 0.88 | TSHR (0.59) | ATMTRPA1TSHRFKBP1ABRD4 | |
| SCHEMBL5716996 | 0.88 | FKBP1A (0.74) | ATMTSHRFKBP1ABRD4TDP1 | |
| SCHEMBL13571295 | 0.87 | FKBP1A (0.77) | ATMTSHRFKBP1AMAPTTDP1 | |
| SCHEMBL13739605 | 0.87 | TSHR (0.73) | ATMTRPA1TSHRFKBP1AMAPT | |
| SCHEMBL13570805 | 0.87 | POLB (0.71) | ATMTSHRFKBP1AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012152983-A1 | PHENYL- SULFONYL DERIVATIVES AS MEDIATORS OF TRPA1 RECEPTOR ACTIVITY FOR THE TREATMENT OF PAIN | ORION CORPORATION (FI) | 2012-11-15 | — | — | WO | claimed |
| EP-2520566-A1 | New Pharmaceutical Compounds | Orion Corporation (FI) | 2012-11-07 | — | — | EP | claimed |
| WO-2012152983-A1 | PHENYL- SULFONYL DERIVATIVES AS MEDIATORS OF TRPA1 RECEPTOR ACTIVITY FOR THE TREATMENT OF PAIN | ORION CORPORATION (FI) | 2012-11-15 | — | — | WO | disclosed |
| EP-2520566-A1 | New Pharmaceutical Compounds | Orion Corporation (FI) | 2012-11-07 | — | — | EP | disclosed |