Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | KDM1A | O60341 | 5/20 | 0.32 |
| ▸ | MAOA | P21397 | 5/20 | 0.32 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10194862 | 0.84 | MEN1 (0.38) | SLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL2160044 | 0.82 | KDM1A (0.44) | SLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL2159199 | 0.82 | HTR3A (0.49) | SLC6A2SLC6A4SLC6A3KDM1AHTR3A | |
| SCHEMBL10292141 | 0.82 | HTR3A (0.49) | SLC6A2SLC6A4SLC6A3KDM1AHTR3A | |
| SCHEMBL25329786 | 0.82 | ESR2 (0.43) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17948228 | 0.81 | SLC18A3 (0.48) | KDM1AMAOAMAOB | |
| SCHEMBL15317743 | 0.79 | HTR2C (0.38) | SLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL4890404 | 0.78 | HTR2C (0.56) | SLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL25212520 | 0.74 | KDM1A (0.45) | KDM1AMAOAMAOB | |
| SCHEMBL31738595 | 0.71 | CYP1A2 (0.40) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158452-A1 | PIPERIDINYL DERIVATIVE AS A MODULATOR OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-12-30 | — | — | WO | disclosed |