Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | HPGD | P15428 | 4/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.73 |
| ▸ | ALB | P02768 | 1/20 | 0.73 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.73 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | TUBB | P07437 | 1/20 | 0.72 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.72 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.72 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.72 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.72 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.72 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.72 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.72 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.72 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.72 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980361 | 0.91 | AADAT (0.70) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3979263 | 0.90 | AADAT (0.71) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9143978 | 0.90 | KDM4E (0.72) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9524517 | 0.90 | KDM4E (0.72) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9147408 | 0.90 | KDM4E (0.72) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9145342 | 0.89 | KDM4E (0.71) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9144491 | 0.89 | KDM4E (0.71) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3976114 | 0.88 | AADAT (0.69) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3977395 | 0.87 | AADAT (0.67) | AADATKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3979177 | 0.87 | AADAT (0.67) | AADATKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306035-A1 | Compounds and Methods for modulating the Silencing of a Polynucleotide of Interest | EMORY UNIVERSITY (US) | 2009-12-10 | — | — | US | disclosed |
| US-20090306035-A1 | Compounds and Methods for modulating the Silencing of a Polynucleotide of Interest | EMORY UNIVERSITY (US) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306035-A1 | Compounds and Methods for modulating the Silencing of a Polynucleotide of Interest | SNRPE, NSUN2, SNRPA | AADAT 2571/4885KDM4E 3182/4885ALDH1A1 3615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.