Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13577600 | 0.89 | HTT (0.34) | HTTSMN1; SMN2MAPTEGFRTDP2 | |
| SCHEMBL3984538 | 0.72 | SMN1; SMN2 (0.40) | HTTSMN1; SMN2MAPTEGFRTDP2 | |
| SCHEMBL3987589 | 0.71 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTEGFRTDP2NSD2 | |
| SCHEMBL3985780 | 0.68 | SMN1; SMN2 (0.39) | SMN1; SMN2MAPTEGFRTDP2NSD2 | |
| SCHEMBL4450954 | 0.67 | MAPK14 (0.32) | MAPTALDH1A1HPGDL3MBTL1GAA | |
| SCHEMBL3988044 | 0.67 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTEGFRTDP2NSD2 | |
| SCHEMBL3985363 | 0.67 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTEGFRTDP2NSD2 | |
| SCHEMBL3985176 | 0.67 | SMN1; SMN2 (0.39) | HTTSMN1; SMN2MAPTEGFRTDP2 | |
| SCHEMBL3985352 | 0.66 | MAPT (0.39) | SMN1; SMN2MAPTEGFRTDP2NSD2 | |
| SCHEMBL3982506 | 0.65 | KDM4E (0.41) | MAPTEGFRKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009154870-A1 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 2009-12-23 | — | — | WO | disclosed |