Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13577600 | 0.77 | HTT (0.34) | ALDH1A1GAAMAPTHPGDL3MBTL1 | |
| SCHEMBL13577604 | 0.67 | HTT (0.34) | ALDH1A1GAAMAPTHPGDL3MBTL1 | |
| SCHEMBL31644360 | 0.61 | MAPT (0.43) | MAPK14MAPTHPGDTDP1L3MBTL1 | |
| SCHEMBL20015193 | 0.58 | ALKBH1 (0.38) | ALDH1A1HPGD | |
| SCHEMBL4578216 | 0.58 | ALDH1A1 (0.41) | ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL3985352 | 0.57 | MAPT (0.39) | ALDH1A1GAAMAPTHPGDTDP1 | |
| SCHEMBL5124464 | 0.57 | GRM5 (0.41) | ALDH1A1HPGD | |
| SCHEMBL17852730 | 0.57 | POU2F2 (0.41) | ALDH1A1 | |
| SCHEMBL17852635 | 0.57 | POU2F2 (0.41) | ALDH1A1GAAHPGD | |
| SCHEMBL17852652 | 0.57 | POU2F2 (0.41) | ALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009154870-A1 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 2009-12-23 | — | — | WO | disclosed |