Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT2 | P23786 | 1/20 | 0.47 |
| ▸ | CPT1A | P50416 | 1/20 | 0.47 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 10/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4333770 | 0.93 | CPT2 (0.53) | CPT2CPT1ACPT1BRAB9ATP53 | |
| SCHEMBL13578018 | 0.92 | CPT2 (0.46) | CPT2CPT1ACPT1BRAB9ATP53 | |
| SCHEMBL13578022 | 0.91 | CPT2 (0.45) | CPT2CPT1ACPT1BRAB9ATP53 | |
| SCHEMBL4327253 | 0.91 | CPT2 (0.45) | CPT2CPT1ACPT1BRAB9ATP53 | |
| SCHEMBL13577917 | 0.89 | RXFP1 (0.42) | CPT2CPT1ACPT1BSMN1; SMN2MAPT | |
| SCHEMBL13577920 | 0.88 | KMT2A (0.46) | CPT2CPT1ACPT1BRAB9ATP53 | |
| SCHEMBL13577916 | 0.87 | ALDH1A1 (0.48) | RAB9ASMN1; SMN2MAPTALDH1A1POLB | |
| SCHEMBL13578020 | 0.87 | CPT2 (0.42) | CPT2CPT1ACPT1BRAB9ATP53 | |
| SCHEMBL13578019 | 0.87 | ATM (0.49) | CPT2CPT1ACPT1BRAB9ATP53 | |
| SCHEMBL13578021 | 0.86 | NPC1 (0.48) | RAB9ATP53SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147121-A1 | CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-10 | — | — | WO | disclosed |