Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | YAP1 | P46937 | 2/20 | 0.56 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PRNP | P04156 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1567522 | 0.91 | MAPT (0.69) | MAPTLMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1887127 | 0.91 | YAP1 (0.66) | MAPTLMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1879167 | 0.91 | MAPT (0.66) | MAPTLMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12639504 | 0.86 | MAPT (0.60) | MAPTLMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1876718 | 0.85 | CYP3A4 (0.70) | MAPTLMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1888843 | 0.81 | SMN1; SMN2 (0.68) | MAPTLMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15189077 | 0.80 | SMN1; SMN2 (0.65) | MAPTLMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15189116 | 0.79 | MAPT (0.63) | MAPTLMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12672326 | 0.79 | MAPT (0.53) | MAPTLMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1887723 | 0.79 | MAPT (0.54) | MAPTLMNACYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150248-A1 | COMPOUNDS WHICH CAN BE USED FOR THE TREATMENT OF CANCERS | CYTOMICS SYSTEMS (FR) | 2009-12-17 | — | — | WO | disclosed |