Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12639506 | 0.91 | LMNA (0.47) | EPHX2GAALMNASMN1; SMN2KMT2A | |
| SCHEMBL12639503 | 0.90 | KMT2A (0.45) | EPHX2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL12639550 | 0.89 | GAA (0.44) | EPHX2GAALMNASMN1; SMN2KMT2A | |
| SCHEMBL12672265 | 0.89 | EPHX2 (0.43) | EPHX2GAALMNASMN1; SMN2KMT2A | |
| SCHEMBL12639581 | 0.89 | KMT2A (0.45) | EPHX2GAALMNASMN1; SMN2KMT2A | |
| SCHEMBL12639608 | 0.89 | EPHX2 (0.46) | EPHX2GAALMNASMN1; SMN2KMT2A | |
| SCHEMBL12639601 | 0.88 | EPHX2 (0.42) | EPHX2GAALMNASMN1; SMN2KMT2A | |
| SCHEMBL12639586 | 0.88 | EPHX2 (0.42) | EPHX2GAALMNASMN1; SMN2KMT2A | |
| SCHEMBL15189094 | 0.88 | GAA (0.52) | EPHX2GAALMNASMN1; SMN2KMT2A | |
| SCHEMBL12639594 | 0.88 | LMNA (0.45) | EPHX2GAALMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150248-A1 | COMPOUNDS WHICH CAN BE USED FOR THE TREATMENT OF CANCERS | CYTOMICS SYSTEMS (FR) | 2009-12-17 | — | — | WO | disclosed |