Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13580828 | 0.87 | NPC1 (0.33) | NPC1KMT2AATMGPR35 | |
| SCHEMBL13580353 | 0.87 | NPC1 (0.33) | NPC1KMT2AATMGPR35PTGS2 | |
| SCHEMBL18877728 | 0.87 | PTGS2 (0.43) | NPC1KMT2AATMGPR35PTGS2 | |
| SCHEMBL13580358 | 0.86 | NPC1 (0.33) | NPC1KMT2AATMGPR35PTGS2 | |
| SCHEMBL13580827 | 0.86 | NPC1 (0.33) | NPC1KMT2AATMGPR35 | |
| SCHEMBL13580348 | 0.86 | NPC1 (0.34) | NPC1KMT2AATMGPR35PTGS2 | |
| SCHEMBL13580361 | 0.84 | APP (0.34) | NPC1KMT2AATMGPR35MAPT | |
| SCHEMBL13580394 | 0.84 | PTGS2 (0.35) | NPC1KMT2AATMGPR35PTGS2 | |
| SCHEMBL13580359 | 0.83 | PTGS2 (0.38) | KMT2APTGS2SMN1; SMN2ACHEMAPT | |
| SCHEMBL13580858 | 0.83 | NPC1 (0.31) | NPC1KMT2AATMGPR35MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090317733-A1 | Quinone Compound, Electrophotographic Photoconductor and Electrophotographic Apparatus | FUJI ELECTRIC DEVICE TECHNOLOGY CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |