Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.45 |
| ▸ | LPL | P06858 | 4/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.45 |
| ▸ | LIPC | P11150 | 5/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1410218 | 0.92 | FFAR4 (0.52) | LIPGLPLFFAR4LIPCNOTUM | |
| SCHEMBL1409535 | 0.92 | FFAR4 (0.52) | LIPGLPLFFAR4LIPCNOTUM | |
| SCHEMBL1410475 | 0.92 | FFAR4 (0.52) | LIPGLPLFFAR4LIPCNOTUM | |
| SCHEMBL1410209 | 0.87 | FFAR4 (0.55) | LIPGLPLFFAR4LIPCNOTUM | |
| SCHEMBL1410693 | 0.87 | FFAR4 (0.55) | LIPGLPLFFAR4LIPCNOTUM | |
| SCHEMBL1410461 | 0.86 | LIPG (0.45) | LIPGLPLFFAR4LIPCNOTUM | |
| SCHEMBL1410506 | 0.84 | DPP4 (0.53) | LIPGLPLFFAR4LIPCNOTUM | |
| SCHEMBL1410566 | 0.84 | FFAR4 (0.44) | LIPGLPLFFAR4LIPCNOTUM | |
| SCHEMBL12210057 | 0.83 | NOTUM (0.63) | LIPGLPLLIPCNOTUM | |
| SCHEMBL1410148 | 0.82 | NOTUM (0.60) | LIPGLPLFFAR4LIPCNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145286-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-12-03 | — | — | WO | disclosed |