Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13582396 | 1.00 | APP (0.43) | APPCA12CA2CA9CA1 | |
| SCHEMBL13581864 | 0.98 | APP (0.41) | APPCA12CA2CA9CA1 | |
| SCHEMBL13582298 | 0.92 | FFAR1 (0.40) | APPCA12CA2CA9CA1 | |
| SCHEMBL13582392 | 0.91 | KCNH2 (0.40) | APPCA12CA2CA9CA1 | |
| SCHEMBL5521992 | 0.91 | FFAR1 (0.39) | APPCA12CA2CA9CA1 | |
| SCHEMBL13581991 | 0.91 | FFAR1 (0.40) | APPCA12CA2CA9CA1 | |
| SCHEMBL13582120 | 0.91 | FFAR1 (0.40) | APPCA12CA2CA9CA1 | |
| SCHEMBL13581998 | 0.91 | FFAR1 (0.40) | APPCA12CA2CA9CA1 | |
| SCHEMBL6671636 | 0.91 | ESR1 (0.42) | CA12CA2CA9CA1MAPT | |
| SCHEMBL5525269 | 0.91 | APP (0.52) | APPCA12CA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7626059-B2 | Multifunctional ethynyl substituted monomers and polyarylene compositions therefrom | DOW GLOBAL TECHNOLOGIES INC. | 2009-12-01 | — | — | US | disclosed |
| US-20090012193-A1 | Multifunctional Ethynyl Substituted Monomers and Polyarylene Compositions Therefrom | DOW GLOBAL TECHNOLOGIES LLC | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012193-A1 | Multifunctional Ethynyl Substituted Monomers and Polyarylene Compositions Therefrom | WEE2, WASF2, WEE1 | APP 3477/4885CA12 4304/4885CA2 4378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.