Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22552745 | 1.00 | BLM (0.45) | BLMTRPV1TRPA1GPR84FFAR1 | |
| SCHEMBL1359074 | 1.00 | BLM (0.45) | BLMTRPV1TRPA1GPR84FFAR1 | |
| SCHEMBL22552743 | 1.00 | BLM (0.45) | BLMTRPV1TRPA1GPR84FFAR1 | |
| SCHEMBL1358682 | 1.00 | BLM (0.45) | BLMTRPV1TRPA1GPR84FFAR1 | |
| SCHEMBL1359573 | 1.00 | BLM (0.45) | BLMTRPV1TRPA1GPR84FFAR1 | |
| SCHEMBL7822400 | 0.85 | GPR84 (0.61) | GPR84FFAR1ABCB1ACE2SPHK1 | |
| SCHEMBL22552585 | 0.85 | GPR84 (0.61) | GPR84FFAR1ABCB1ACE2SPHK1 | |
| SCHEMBL7083484 | 0.85 | GPR84 (0.61) | GPR84FFAR1ABCB1ACE2SPHK1 | |
| SCHEMBL1271078 | 0.85 | GPR84 (0.61) | GPR84FFAR1ABCB1ACE2SPHK1 | |
| SCHEMBL7080515 | 0.85 | GPR84 (0.61) | GPR84FFAR1ABCB1ACE2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309276-B2 | Synthetic lipid A derivative | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2016-04-12 | — | — | US | disclosed |
| US-20140011987-A1 | Synthetic Lipid A Derivative | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2014-01-09 | — | — | US | disclosed |
| US-8563523-B2 | Synthetic lipid A derivative | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-10-22 | — | — | US | disclosed |
| US-20110280893-A9 | SYNTHETIC LIPID A DERIVATIVE | UNIVERSITY OF GEORGIA RESEACH FOUNDATION, INC (US) | 2011-11-17 | — | — | US | disclosed |
| US-20100221269-A1 | SYNTHETIC LIPID A DERIVATIVE | UNIVERSITY OF GEORGIA RESEACH FOUNDATION, INC (US) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011987-A1 | Synthetic Lipid A Derivative | DDOST, STT3A, UGCG | BLM 2996/4885TRPV1 4222/4885TRPA1 4685/4885 |
| US-20110280893-A9 | SYNTHETIC LIPID A DERIVATIVE | DDOST, STT3A, UGCG | BLM 2996/4885TRPV1 4222/4885TRPA1 4685/4885 |
| US-20100221269-A1 | SYNTHETIC LIPID A DERIVATIVE | DDOST, STT3A, UGCG | BLM 2996/4885TRPV1 4222/4885TRPA1 4685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.