SCHEMBL13586337

SCHEMBL13586337

CCOc1ccc(C2CCC(/C=C/c3ccc(-c4ccc(OC)cc4)c(F)c3F)CC2)c(F)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.35
HTT P42858 1/20 0.35
MAPT P10636 2/20 0.34
FFAR4 Q5NUL3 2/20 0.33
FFAR1 O14842 1/20 0.33
ALOX5AP P20292 3/20 0.33
FEN1 P39748 3/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
RAB9A P51151 1/20 0.33
CPS1 P31327 2/20 0.32
CAMKK1 Q8N5S9 1/20 0.32
CAMKK2 Q96RR4 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
GPR35 Q9HC97 1/20 0.32
GPR55 Q9Y2T6 1/20 0.32
NR1I2 O75469 1/20 0.32
IDO1 P14902 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14765855 0.95 FFAR4 (0.37) LMNAFFAR4FFAR1ALOX5APFEN1
SCHEMBL13586590 0.93 LMNA (0.35) LMNAHTTMAPTFFAR4FFAR1
SCHEMBL12734340 0.93 FFAR4 (0.33) LMNAMAPTFFAR4FFAR1ALOX5AP
SCHEMBL12716200 0.92 CYP1A2 (0.36) ALOX5APFEN1IDO1ERN1
SCHEMBL12734331 0.92 FFAR4 (0.33) FFAR4FFAR1ALOX5APFEN1CAMKK1
SCHEMBL12734337 0.91 FFAR4 (0.34) FFAR4FFAR1ALOX5APFEN1CAMKK1
SCHEMBL14765734 0.91 FFAR4 (0.40) FFAR4FFAR1CAMKK1CAMKK2HMOX1
SCHEMBL12716432 0.90 FFAR4 (0.32) FFAR4FFAR1CAMKK1CAMKK2HMOX1
SCHEMBL14765904 0.90 FFAR4 (0.34) LMNAMAPTFFAR4FFAR1NPC1
SCHEMBL12716198 0.90 FFAR4 (0.32) MAPTFFAR4FFAR1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed
WO-2009150966-A1 TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT チッソ株式会社 (JP) 2009-12-17 WO disclosed