SCHEMBL1358699

SCHEMBL1358699

C[Ni](C)C1=CC=CC1.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
DRD1 P21728 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL969032 0.79
SCHEMBL28830996 0.76 CYP3A4 (0.31) CYP3A4TDP1
SCHEMBL3011683 0.75 CYP3A4 (0.50) CYP3A4TDP1ESR1ESR2DRD1
SCHEMBL17157063 0.73 CYP3A4 (0.48) CYP3A4TDP1ESR1ESR2DRD1
SCHEMBL1929940 0.73 CYP3A4 (0.48) CYP3A4TDP1ESR1ESR2DRD1
SCHEMBL28587099 0.73 CYP3A4 (0.48) CYP3A4TDP1ESR1ESR2DRD1
SCHEMBL10591398 0.73 CYP3A4 (0.48) CYP3A4TDP1ESR1ESR2DRD1
SCHEMBL18641305 0.73 CYP3A4 (0.48) CYP3A4TDP1ESR1ESR2DRD1
SCHEMBL7539350 0.73 CYP3A4 (0.48) CYP3A4TDP1ESR1ESR2DRD1
SCHEMBL4805147 0.73 CYP3A4 (0.48) CYP3A4TDP1ESR1ESR2DRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2391661-B1 NORBORNENE COPOLYMER AND PRODUCTION METHOD THEREOF SHOWA DENKO KK (JP) 2013-07-31 EP disclosed
EP-2599801-A1 CATALYST COMPOSITION, METHOD FOR PRODUCING NORBORNENE COPOLYMER USING CATALYST COMPOSITION, NORBORNENE COPOLYMER, AND HEAT RESISTANT FILM USING COPOLYMER Showa Denko K.K. (JP) 2013-06-05 EP disclosed
US-20130116113-A1 CATALYST COMPOSITION, PRODUCTION PROCESS FOR NORBORNENE BASE COPOLYMER BY USING CATALYST COMPOSITION, NORBORNENE BASE COPOLYMER AND HEAT RESISTANT FILM PREPARED BY USING THE SAME SHOWA DENKO K.K. (JP) 2013-05-09 US disclosed
US-8163860-B2 Norbornene copolymer and production method thereof SHOWA DENKO K.K. (JP) 2012-04-24 US disclosed
US-20110282014-A1 NORBORNENE COPOLYMER AND PRODUCTION METHOD THEREOF RIKEN (JP) 2011-11-17 US disclosed
EP-2213691-A1 Cycloolefin addition polymer and making method Shin-Etsu Chemical Co., Ltd. (JP) 2010-08-04 EP disclosed
US-20100190950-A1 CYCLOOLEFIN ADDITION POLYMER AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-07-29 US disclosed