Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14624134 | 0.83 | CYP3A4 (0.55) | CYP3A4 | |
| SCHEMBL13003259 | 0.82 | CYP3A4 (0.53) | CYP3A4 | |
| SCHEMBL14469248 | 0.82 | CYP3A4 (0.61) | CYP3A4 | |
| SCHEMBL8230524 | 0.82 | CYP3A4 (0.61) | CYP3A4 | |
| SCHEMBL13003871 | 0.80 | CYP3A4 (0.57) | CYP3A4 | |
| SCHEMBL8231191 | 0.79 | CYP3A4 (0.53) | CYP3A4 | |
| SCHEMBL18985960 | 0.79 | TBK1 (0.60) | CYP3A4 | |
| SCHEMBL13391706 | 0.79 | CYP3A4 (0.63) | CYP3A4 | |
| SCHEMBL14456965 | 0.79 | CYP3A4 (0.52) | CYP3A4 | |
| SCHEMBL13003546 | 0.79 | CYP3A4 (0.52) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902046-B1 | PIPERIDINE DERIVATIVES USEFUL AS HISTAMINE H3 ANTAGONISTS | SCHERING CORP (US) | 2009-12-02 | — | — | EP | disclosed |