Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13003562 | 0.94 | CYP3A4 (0.50) | CYP3A4EPHX2DRD2DRD4DRD3 | |
| SCHEMBL13003561 | 0.84 | EPHX2 (0.55) | DCUN1D1CYP3A4EPHX2DRD2DRD4 | |
| SCHEMBL13003546 | 0.81 | CYP3A4 (0.52) | CYP3A4 | |
| SCHEMBL13003343 | 0.80 | CYP3A4 (0.53) | CYP3A4 | |
| SCHEMBL13003648 | 0.80 | CYP3A4 (0.53) | CYP3A4 | |
| SCHEMBL13003259 | 0.79 | CYP3A4 (0.53) | CYP3A4 | |
| SCHEMBL13003568 | 0.79 | CYP3A4 (0.53) | CYP3A4 | |
| SCHEMBL14469248 | 0.78 | CYP3A4 (0.61) | CYP3A4 | |
| SCHEMBL13003487 | 0.77 | DRD2 (0.56) | DCUN1D1CYP3A4EPHX2MAPTDRD2 | |
| SCHEMBL13003707 | 0.77 | CYP3A4 (0.51) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902046-B1 | PIPERIDINE DERIVATIVES USEFUL AS HISTAMINE H3 ANTAGONISTS | SCHERING CORP (US) | 2009-12-02 | — | — | EP | disclosed |