Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.50 |
| ▸ | MMP1 | P03956 | 4/20 | 0.50 |
| ▸ | MMP3 | P08254 | 4/20 | 0.50 |
| ▸ | CETP | P11597 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1359365 | 1.00 | MMP2 (0.50) | MMP2MMP1MMP3CETPCNR2 | |
| SCHEMBL1358861 | 1.00 | MMP2 (0.50) | MMP2MMP1MMP3CETPCNR2 | |
| SCHEMBL29893945 | 1.00 | MMP2 (0.50) | MMP2MMP1MMP3CETPCNR2 | |
| SCHEMBL4969361 | 1.00 | MMP2 (0.50) | MMP2MMP1MMP3CETPCNR2 | |
| SCHEMBL1359364 | 1.00 | MMP2 (0.50) | MMP2MMP1MMP3CETPCNR2 | |
| SCHEMBL1358863 | 1.00 | MMP2 (0.50) | MMP2MMP1MMP3CETPCNR2 | |
| SCHEMBL1358859 | 1.00 | MMP2 (0.50) | MMP2MMP1MMP3CETPCNR2 | |
| Hydrochloric Acid SCHEMBL2679110 | 0.99 | MMP2 (0.49) | MMP2MMP1MMP3CETP | |
| Hydrochloric Acid SCHEMBL2679113 | 0.99 | MMP2 (0.49) | MMP2MMP1MMP3CETP | |
| SCHEMBL30873579 | 0.99 | MMP2 (0.48) | MMP2MMP1MMP3CETPCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309276-B2 | Synthetic lipid A derivative | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2016-04-12 | — | — | US | disclosed |
| US-20140011987-A1 | Synthetic Lipid A Derivative | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2014-01-09 | — | — | US | disclosed |
| US-8563523-B2 | Synthetic lipid A derivative | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-10-22 | — | — | US | disclosed |
| US-20110280893-A9 | SYNTHETIC LIPID A DERIVATIVE | UNIVERSITY OF GEORGIA RESEACH FOUNDATION, INC (US) | 2011-11-17 | — | — | US | disclosed |
| US-20100221269-A1 | SYNTHETIC LIPID A DERIVATIVE | UNIVERSITY OF GEORGIA RESEACH FOUNDATION, INC (US) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011987-A1 | Synthetic Lipid A Derivative | DDOST, STT3A, UGCG | MMP2 4383/4885MMP1 4857/4885MMP3 3895/4885 |
| US-20110280893-A9 | SYNTHETIC LIPID A DERIVATIVE | DDOST, STT3A, UGCG | MMP2 4383/4885MMP1 4857/4885MMP3 3895/4885 |
| US-20100221269-A1 | SYNTHETIC LIPID A DERIVATIVE | DDOST, STT3A, UGCG | MMP2 4383/4885MMP1 4857/4885MMP3 3895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.