SCHEMBL13589239

SCHEMBL13589239

c1ccc2c(c1)-c1ccccc1C2c1ccc(C2(c3ccc(-n4c5ccccc5c5ccccc54)cc3)c3ccccc3C3(CC3)c3ccccc32)cc1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
OPRK1 P41145 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HDAC4 P56524 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16848799 0.86 HDAC4 (0.40) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL13589240 0.85 KDM4E (0.47) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL13172988 0.83 KDM4E (0.37) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL30361035 0.81 L3MBTL1 (0.52) KDM4EATML3MBTL1MEN1MAPT
SCHEMBL28426512 0.81 L3MBTL1 (0.52) KDM4EATML3MBTL1MEN1MAPT
SCHEMBL12156940 0.77 HDAC4 (0.48) KDM4EATML3MBTL1MEN1MAPT
SCHEMBL1334632 0.76 KDM4E (0.52) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL29419043 0.76 KDM4E (0.52) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL30571079 0.76 KDM4E (0.52) KDM4EATML3MBTL1MEN1LMNA
SCHEMBL19238744 0.75 L3MBTL1 (0.44) KDM4EATML3MBTL1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2765174-A1 Organic electroluminescent element, and display and illuminator Konica Minolta Holdings, Inc. (JP) 2014-08-13 EP disclosed
EP-2762546-A1 Organic electroluminescent element, and display and illuminator Konica Minolta Holdings, Inc. (JP) 2014-08-06 EP disclosed
EP-2759585-A1 Organic electroluminescent element, and display and illuminator Konica Minolta Business Technologies, Inc. (JP) 2014-07-30 EP disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed