Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.42 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL2564207 | 0.90 | F7 (0.56) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Adenine SCHEMBL22748483 | 0.90 | F7 (0.56) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Adenine SCHEMBL15699 | 0.90 | F7 (0.56) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Adenine SCHEMBL8414752 | 0.89 | F7 (0.52) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Adenine SCHEMBL23531099 | 0.89 | F7 (0.55) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Adenine SCHEMBL11807677 | 0.89 | F7 (0.55) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Adenine SCHEMBL7712105 | 0.89 | F7 (0.55) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Adenine SCHEMBL28614873 | 0.89 | F7 (0.55) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Adenine SCHEMBL23859925 | 0.89 | F7 (0.55) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Adenine SCHEMBL22129922 | 0.89 | F7 (0.55) | ALDH1A1APPGAAHCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113151378-B | Method for preparing nucleoside, nicotinic acid adenine dinucleotide and nicotinic acid mononucleotide of nicotinic acid or derivative thereof, enzyme composition and application | 百瑞全球有限公司 | 2023-06-06 | — | — | CN | claimed |
| US-20220409647-A1 | COMPOSITIONS, METHODS AND KITS FOR ALTERING ADIPOCYTES | NUSIRT SCIENCES, INC. | 2022-12-29 | — | — | US | claimed |
| US-20220056458-A1 | GENETICALLY MODIFIED MICROORGANISM AND METHOD BOTH FOR PRODUCING NICOTINAMIDE DERIVATIVE, AND VECTOR FOR USE IN SAME | TEIJIN LIMITED (JP) | 2022-02-24 | — | — | US | claimed |
| EP-2968333-B1 | LEUCINE AND NICOTINIC ACID FOR THE REDUCTION OF LIPID LEVELS | NUSIRT SCIENCES INC (US) | 2022-01-12 | — | — | EP | claimed |
| EP-3901272-A1 | GENETICALLY MODIFIED MICROORGANISM AND METHOD BOTH FOR PRODUCING NICOTINAMIDE DERIVATIVE, AND VECTOR FOR USE IN SAME | Teijin Limited (JP) | 2021-10-27 | — | — | EP | claimed |
| WO-2021096882-A1 | COMPOSITIONS, METHODS AND KITS FOR ALTERING ADIPOCYTES | NUSIRT SCIENCES, INC. (US) | 2021-05-20 | — | — | WO | claimed |
| CN-109475572-A | Method for enhancing liver regeneration | 宾夕法尼亚州大学信托人 | 2019-03-15 | — | — | CN | claimed |
| CN-108884483-A | The micro-organisms of niacin riboside | 帝斯曼知识产权资产管理有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-108473948-A | The micro-organisms of niacinamide riboside | 帝斯曼知识产权资产管理有限公司 | 2018-08-31 | — | — | CN | claimed |
| US-20180235917-A1 | COMPOSITIONS, METHODS AND KITS FOR TREATMENT OF DIABETES AND/OR HYPERLIPIDEMIA | NUSIRT SCIENCES, INC. (US) | 2018-08-23 | — | — | US | claimed |
| WO-2016049236-A1 | COMPOSITIONS, METHODS AND KITS FOR TREATMENT OF DIABETES AND/OR HYPERLIPIDEMIA | NUSIRT SCIENCES, INC. (US) | 2016-03-31 | — | — | WO | claimed |
| EP-2968333-A1 | LEUCINE AND NICOTINIC ACID REDUCES LIPID LEVELS | Nusirt Sciences, Inc. (US) | 2016-01-20 | — | — | EP | claimed |
| US-20160008329-A1 | LEUCINE AND NICOTINIC ACID REDUCES LIPID LEVELS | NUSIRT SCIENCES, INC. | 2016-01-14 | — | — | US | claimed |
| CN-105228627-A | Leucine and nicotinic acid reduce lipid level | NUSIRT SCIENCES INC | 2016-01-06 | — | — | CN | claimed |
| CN-103108640-B | Comprise pharmacy or the cosmetic combination of the derivant of nicotinate adenine dinucleotide phosphoric acid or this nicotinate adenine dinucleotide phosphoric acid | DAMY CHEMICAL Co.,Ltd. (KR) | 2015-09-09 | — | — | CN | claimed |
| WO-2014152016-A1 | LEUCINE AND NICOTINIC ACID REDUCES LIPID LEVELS | NUSIRT SCIENCES, INC. (US) | 2014-09-25 | — | — | WO | claimed |
| CN-103108640-A | Pharmaceutical or cosmetic composition containing nicotinic acid adenine dinucleotide phosphate or derivative thereof | DAMY CHEMICAL CO LTD | 2013-05-15 | — | — | CN | claimed |
| US-8133872-B2 | Use of nicotinic acid adenine dinucleotide phosphate or derivative thereof as agent for treating type-2 diabetes | INDUSTRIAL COOPERATION FOUNDATION, CHONBUK NATIONAL UNIVERSITY (KR) | 2012-03-13 | — | — | US | claimed |
| CN-1198138-C | Enzyme electrode | ASAHI CHEMICAL IND (JP) | 2005-04-20 | — | — | CN | claimed |
| CN-1452717-A | Enzyme electrode | ASAHI CHEMICAL IND (JP) | 2003-10-29 | — | — | CN | claimed |