Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.59 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 6/20 | 0.40 |
| ▸ | LOX | P28300 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1348600 | 0.78 | — | — | |
| SCHEMBL10157517 | 0.77 | LOXL2 (0.61) | LOXL2LOXRECQLLOXL3FFAR1 | |
| SCHEMBL7922770 | 0.76 | LOXL2 (0.50) | LOXL2 | |
| SCHEMBL501336 | 0.74 | LOXL2 (0.49) | LOXL2KCNQ2CYP3A4ALOX15TSHR | |
| SCHEMBL3255782 | 0.74 | LOXL2 (0.49) | LOXL2KCNQ2CYP3A4ALOX15TSHR | |
| SCHEMBL29962624 | 0.74 | LOXL2 (0.49) | LOXL2KCNQ2CYP3A4ALOX15TSHR | |
| SCHEMBL1390752 | 0.74 | LOXL2 (0.49) | LOXL2TSHRKCNH3RECQLFFAR1 | |
| SCHEMBL864046 | 0.74 | LOXL2 (0.49) | LOXL2KCNQ2CYP3A4ALOX15TSHR | |
| SCHEMBL2642497 | 0.74 | — | — | |
| SCHEMBL7413054 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709037-B1 | HIV PROTEASE INHIBITING SULFONAMIDES | ABBOTT LAB (US) | 2009-12-23 | — | — | EP | disclosed |