Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964043 | 1.00 | KMT2A (0.41) | KMT2APOLBNPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL914451 | 0.99 | KMT2A (0.41) | KMT2APOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL6959363 | 0.92 | KMT2A (0.35) | KMT2ARAB9AALDH1A1MAPTSRD5A2 | |
| SCHEMBL6959492 | 0.92 | ALDH1A1 (0.37) | KMT2AALDH1A1MAPTSRD5A2 | |
| Hydrochloric Acid SCHEMBL915859 | 0.91 | ALDH1A1 (0.37) | KMT2AALDH1A1MAPTSRD5A2 | |
| Hydrochloric Acid SCHEMBL914770 | 0.91 | KMT2A (0.35) | KMT2ANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL914437 | 0.90 | KMT2A (0.41) | KMT2APOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL6962655 | 0.90 | MAOB (0.37) | KMT2AALDH1A1KDM4EDRD2DRD3 | |
| SCHEMBL13593469 | 0.90 | MAOB (0.37) | KMT2AALDH1A1KDM4EDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL914376 | 0.89 | MAOB (0.36) | KMT2AALDH1A1KDM4EMAPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | disclosed |