Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | GMNN | O75496 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.62 |
| ▸ | BLM | P54132 | 2/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1427359 | 1.00 | CYP1A2 (0.64) | CYP1A2MEN1KMT2AMAPK1LMNA | |
| SCHEMBL2517754 | 0.85 | CYP1A2 (0.69) | CYP1A2MEN1KMT2AMAPK1LMNA | |
| SCHEMBL22116167 | 0.83 | CYP1A2 (0.82) | CYP1A2MEN1KMT2AMAPK1LMNA | |
| SCHEMBL5421345 | 0.83 | MEN1 (0.69) | CYP1A2MEN1KMT2AMAPK1LMNA | |
| SCHEMBL5421346 | 0.83 | MEN1 (0.69) | CYP1A2MEN1KMT2AMAPK1LMNA | |
| Hydrochloric Acid SCHEMBL10491645 | 0.83 | MAPT (0.67) | CYP1A2MEN1KMT2AMAPK1LMNA | |
| SCHEMBL22057079 | 0.83 | CYP1A2 (0.66) | CYP1A2MEN1KMT2AMAPK1LMNA | |
| SCHEMBL26640789 | 0.82 | CYP1A2 (0.69) | CYP1A2MEN1KMT2AMAPK1LMNA | |
| Butyryl-Carnitine SCHEMBL12137158 | 0.82 | CYP1A2 (0.79) | CYP1A2MEN1KMT2AMAPK1LMNA | |
| Butyryl-Carnitine SCHEMBL12283483 | 0.82 | CYP1A2 (0.79) | CYP1A2MEN1KMT2AMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728037-B2 | Alpha-ketoglutarates of active ingredients and compositions containing same | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2010-06-01 | — | — | US | claimed |
| EP-1409449-B1 | ALPHA-KETOGLUTARATES OF ACTIVE INGREDIENTS AND COMPOSITIONS CONTAINING SAME | SIGMA TAU IND FARMACEUTI (IT) | 2008-01-09 | — | — | EP | claimed |
| US-20060241181-A1 | Alpha-ketoglutarates of active ingredients and compositions containing same | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A (IT) | 2006-10-26 | — | — | US | claimed |
| US-20040192775-A1 | Alpha-ketoglutarates of active ingredients and compositions containing same | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-09-30 | — | — | US | claimed |
| EP-1409449-A1 | ALPHA-KETOGLUTARATES OF ACTIVE INGREDIENTS AND COMPOSITIONS CONTAINING SAME | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2004-04-21 | — | — | EP | claimed |
| WO-2003010131-A1 | ALPHA-KETOGLUTARATES OF ACTIVE INGREDIENTS AND COMPOSITIONS CONTAINING SAME | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2003-02-06 | — | — | WO | claimed |
| US-8067468-B2 | L-carnitine and alkanoyl L-carnitine phytates and process for preparing the same | SCIAN LABORATORIES, LLC | 2011-11-29 | — | — | US | disclosed |
| US-20100317890-A1 | L-carnitine and alkanoyl L-carnitine phytates and process for preparing the same | SCIAN LABORATORIES, LLC (US) | 2010-12-16 | — | — | US | disclosed |
| CN-101903020-A | L-carnitine phytate and alkanoyl L-carnitine phytate and preparation thereof | SCIAN LAB LLC | 2010-12-01 | — | — | CN | disclosed |
| US-7728037-B2 | Alpha-ketoglutarates of active ingredients and compositions containing same | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2010-06-01 | — | — | US | disclosed |
| EP-1409449-B1 | ALPHA-KETOGLUTARATES OF ACTIVE INGREDIENTS AND COMPOSITIONS CONTAINING SAME | SIGMA TAU IND FARMACEUTI (IT) | 2008-01-09 | — | — | EP | disclosed |
| US-20060241181-A1 | Alpha-ketoglutarates of active ingredients and compositions containing same | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A (IT) | 2006-10-26 | — | — | US | disclosed |
| US-20040192775-A1 | Alpha-ketoglutarates of active ingredients and compositions containing same | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-09-30 | — | — | US | disclosed |
| EP-1409449-A1 | ALPHA-KETOGLUTARATES OF ACTIVE INGREDIENTS AND COMPOSITIONS CONTAINING SAME | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003010131-A1 | ALPHA-KETOGLUTARATES OF ACTIVE INGREDIENTS AND COMPOSITIONS CONTAINING SAME | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2003-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317890-A1 | L-carnitine and alkanoyl L-carnitine phytates and process for preparing the same | CPT1A, CPT1B, SLC25A20 | CYP1A2 2417/4885MEN1 330/4885KMT2A 1438/4885 |
| US-20040192775-A1 | Alpha-ketoglutarates of active ingredients and compositions containing same | GCDH, SLC25A20, GLS | CYP1A2 2514/4885MEN1 1922/4885KMT2A 454/4885 |
| US-20060241181-A1 | Alpha-ketoglutarates of active ingredients and compositions containing same | GCDH, SLC25A20, GLS | CYP1A2 2514/4885MEN1 1922/4885KMT2A 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.