Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4118988 | 0.87 | ACHE (0.37) | ACHETLR9TLR8TLR7BCHE | |
| SCHEMBL13596019 | 0.87 | ACHE (0.45) | ACHETLR9TLR8TLR7BCHE | |
| SCHEMBL13596009 | 0.86 | ACHE (0.52) | ACHEBCHEHRH3 | |
| Hydrochloric Acid SCHEMBL9411371 | 0.84 | ACHE (0.48) | ACHETLR9TLR8TLR7BCHE | |
| SCHEMBL4125654 | 0.82 | SLC6A4 (0.43) | ACHEBCHEKHKSLC6A4 | |
| SCHEMBL13596028 | 0.81 | ACHE (0.45) | ACHETLR9TLR8TLR7BCHE | |
| SCHEMBL4132239 | 0.81 | ACHE (0.40) | ACHEBCHEHRH3SLC6A4 | |
| SCHEMBL4132482 | 0.80 | ACHE (0.41) | ACHEBCHEKHKSLC6A4 | |
| Hydrochloric Acid SCHEMBL9411179 | 0.78 | ACHE (0.42) | ACHETLR9TLR8TLR7HRH3 | |
| SCHEMBL4115246 | 0.76 | KDM1A (0.36) | ACHEBCHEHRH3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | NR1I2, NR1I3, NR0B1 | ACHE 3716/4885TLR9 1433/4885TLR8 2219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.