Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 2/20 | 0.32 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13596064 | 0.87 | ACHE (0.40) | ACHEBCHENMT1 | |
| SCHEMBL4120928 | 0.84 | ACHE (0.38) | ACHEBCHENMT1KHKSLC6A4 | |
| SCHEMBL4120266 | 0.84 | ACHE (0.38) | ACHEBCHENMT1KHKSLC6A4 | |
| SCHEMBL4120262 | 0.84 | ACHE (0.38) | ACHEBCHENMT1KHKSLC6A4 | |
| SCHEMBL13596028 | 0.83 | ACHE (0.45) | ACHEBCHEKHKSLC6A4HRH3 | |
| SCHEMBL4112878 | 0.83 | ACHE (0.37) | ACHEBCHEKHKSLC6A4HRH3 | |
| SCHEMBL4112880 | 0.83 | ACHE (0.37) | ACHEBCHEKHKSLC6A4HRH3 | |
| SCHEMBL4113234 | 0.83 | ACHE (0.37) | ACHEBCHEKHKSLC6A4HRH3 | |
| SCHEMBL13596062 | 0.81 | ACHE (0.36) | ACHEBCHEKHKSLC6A4HRH3 | |
| SCHEMBL4125592 | 0.78 | ACHE (0.38) | ACHEBCHEKHKSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | NR1I2, NR1I3, NR0B1 | ACHE 3716/4885BCHE 2215/4885NMT1 2260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.