Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.44 |
| ▸ | S100A10 | P60903 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844659 | 0.83 | MAOB (0.52) | MAOBMAOAGAAMAPTRAB9A | |
| SCHEMBL13392603 | 0.82 | S1PR1 (0.48) | MAOBMAOAHTR2CHTR6CYP4F2 | |
| SCHEMBL13285041 | 0.82 | BCHE (0.51) | MAOBMAOACYP4F2CYP4A11BCHE | |
| SCHEMBL13596044 | 0.80 | MAPT (0.65) | MAOBGAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27903112 | 0.80 | LCK (0.56) | MAOBMAOACYP4F2CYP4A11BCHE | |
| SCHEMBL13596117 | 0.80 | MAOB (0.54) | MAOBMAOAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL13596041 | 0.80 | MAOB (0.67) | MAOBMAOASMN1; SMN2L3MBTL1NR4A2 | |
| SCHEMBL3175420 | 0.79 | MAOB (0.61) | MAOBMAOAGAAMAPTRAB9A | |
| SCHEMBL1563616 | 0.79 | NR4A2 (0.50) | MAOBMAOASMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL13596039 | 0.78 | NR4A2 (0.52) | MAOBSMN1; SMN2NR4A2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318389-A1 | AGONISTS OF THE SPHINGOSINE-1 PHOSPHATE RECEPTOR | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318389-A1 | AGONISTS OF THE SPHINGOSINE-1 PHOSPHATE RECEPTOR | S1PR1, S1PR3, S1PR5 | MAOB 4235/4885MAOA 4435/4885GAA 3693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.