SCHEMBL1359637

SCHEMBL1359637

C[Sn](C)(C)c1c(F)cc(F)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.31
CA2 P00918 3/20 0.31
CA4 P22748 2/20 0.31
CA12 O43570 1/20 0.31
CA7 P43166 1/20 0.31
CA13 Q8N1Q1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1358916 0.83 CA1 (0.33) CA1CA2CA4CA12CA7
SCHEMBL3721700 0.73
SCHEMBL5701891 0.72 RAPGEF4 (0.33) CA1CA12
SCHEMBL5701821 0.72 CA1 (0.33) CA1CA2CA4CA12CA7
Tetramethylammonium Ion SCHEMBL27610804 0.71 CA1 (0.36) CA1CA2CA4CA12CA7
SCHEMBL7702552 0.69 CA1 (0.43) CA1CA2CA4CA12CA7
SCHEMBL41646 0.69 CA1 (0.43) CA1CA2CA4CA12CA7
SCHEMBL5637066 0.68 TSHR (0.35)
SCHEMBL7607898 0.68
Methyl Alcohol SCHEMBL27510918 0.67 CA1 (0.43) CA1CA2CA4CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507707-B2 Regioselective catalytic conversion of hydrocarbons to versatile synthetic reagents via C-H bond functionalization UNIVERSITY OF WINDSOR (CA) 2013-08-13 US disclosed
US-20110282087-A1 Regioselective catalytic conversion of hydrocarbons to versatile synthetic reagents via C-H bond functionalization UNIVERSITY OF WINDSOR (CA) 2011-11-17 US disclosed
US-RE39679-E1 Substituted heterocycle fused gamma-carbolines BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2007-06-05 US disclosed
US-6713471-B1 SUCH AS TERT-BUTYL-1-METHYL-6,7,9,12-TETRAHYDRO-5H-PYRIDO-(4,3-B)(1,4) THIAZEPINO(2,3,4-HI)INDOLE-11(10H)-CARBOXYLATE; SEROTONIN AGONISTS AND ANTAGONISTS; CENTRAL NERVOUS SYSTEM DISORDERS BRISTOL-MYERS SQUIBB PHARMA COMPANY 2004-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110282087-A1 Regioselective catalytic conversion of hydrocarbons to versatile synthetic reagents via C-H bond functionalization AHR, HRH4, HRH3 CA1 1417/4885CA2 2457/4885CA4 297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.