Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDK | P21741 | 6/20 | 0.54 |
| ▸ | BDNF | P23560 | 3/20 | 0.54 |
| ▸ | PTN | P21246 | 2/20 | 0.54 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | FGF2 | P09038 | 6/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.36 |
| ▸ | BMP2 | P12643 | 2/20 | 0.35 |
| ▸ | VEGFA | P15692 | 2/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.35 |
| ▸ | SHH | Q15465 | 2/20 | 0.35 |
| ▸ | IFNG | P01579 | 1/20 | 0.35 |
| ▸ | PF4 | P02776 | 1/20 | 0.35 |
| ▸ | CCL2 | P13500 | 1/20 | 0.35 |
| ▸ | SELP | P16109 | 1/20 | 0.35 |
| ▸ | BMP6 | P22004 | 1/20 | 0.35 |
| ▸ | CCL11 | P51671 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.35 |
| ▸ | SERPINC1 | P01008 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13431447 | 0.90 | MDK (0.58) | MDKBDNFPTNF10FGF2 | |
| SCHEMBL13596935 | 0.90 | MDK (0.58) | MDKBDNFPTNF10FGF2 | |
| SCHEMBL13431463 | 0.87 | MDK (0.56) | MDKBDNFPTNF10FGF2 | |
| SCHEMBL13321923 | 0.86 | BDNF (0.54) | MDKBDNFPTNF10FGF2 | |
| SCHEMBL14414765 | 0.84 | BDNF (0.53) | MDKBDNFPTNF10FGF2 | |
| SCHEMBL13321927 | 0.84 | MDK (0.51) | MDKBDNFPTNF10FGF2 | |
| SCHEMBL13596899 | 0.81 | MDK (0.50) | MDKBDNFPTNF10FGF2 | |
| SCHEMBL13596930 | 0.81 | MDK (0.54) | MDKBDNFPTNF10FGF2 | |
| SCHEMBL13431400 | 0.79 | MDK (0.55) | MDKBDNFPTNF10FGF2 | |
| SCHEMBL13596864 | 0.79 | MDK (0.72) | MDKBDNFPTNF10FGF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638503-B2 | Small molecule stimulators of neuronal growth | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2009-12-29 | — | — | US | disclosed |