Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.86 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL2849383 | 1.00 | — | — | |
| Alcohol SCHEMBL8050582 | 1.00 | TSHR (0.86) | TSHRALDH1A1NFKB1KCNA1SMN1; SMN2 | |
| Alcohol SCHEMBL21062125 | 1.00 | — | — | |
| Alcohol SCHEMBL709842 | 1.00 | — | — | |
| Alcohol SCHEMBL11442066 | 0.94 | — | — | |
| Alcohol SCHEMBL9207184 | 0.94 | — | — | |
| Alcohol SCHEMBL8568674 | 0.94 | — | — | |
| Alcohol SCHEMBL18825542 | 0.94 | — | — | |
| Alcohol SCHEMBL7260944 | 0.94 | — | — | |
| Alcohol SCHEMBL12803525 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117898288-A | Redox-responsive pesticide prodrug composite microcapsule and preparation method thereof | 上海师范大学 | 2024-04-19 | — | — | CN | claimed |
| CN-112121844-A | Preparation method of molybdenum disulfide carbide/sulfur-doped carbon nitride heterojunction and application of molybdenum disulfide carbide/sulfur-doped carbon nitride heterojunction in degradation of organic pollutant rhodamine B | 江西科技师范大学 | 2020-12-25 | — | — | CN | claimed |
| WO-2019076178-A1 | DEGRADATION TIME CONTROLLABLE AND BREAKING ELONGATION ADJUSTABLE MEDICAL DEGRADABLE POLYURETHANE | 凯斯蒂南京医疗器械有限公司 | 2019-04-25 | — | — | WO | claimed |
| CN-105816904-B | A kind of medical antibacterial gauze | 绍兴易邦医用品有限公司 | 2018-11-16 | — | — | CN | claimed |
| CN-104176737-B | Method for recovering silicon powder from cut mortar waste | 佳明新材料科技有限公司 | 2017-02-08 | — | — | CN | claimed |
| CN-105920683-A | Titanium nail used for stomach diseases and being capable of preventing bacterial infection | 李蒙 | 2016-09-07 | — | — | CN | claimed |
| CN-105832462-A | Antibacterial sanitary napkin | 顾银凤 | 2016-08-10 | — | — | CN | claimed |
| CN-105816904-A | Medical antimicrobial gauze | 顾银凤 | 2016-08-03 | — | — | CN | claimed |
| CN-105288584-A | Preparation method of intelligent antibacterial polypeptide coating layer | UNIV SOUTHEAST | 2016-02-03 | — | — | CN | claimed |
| US-4335240-A | Process for cyclization | ELI LILLY AND COMPANY (US) | 1982-06-15 | — | — | US | claimed |
| JP-6340614-A | — | — | None | — | — | JP | disclosed |
| JP-6340614-A | — | — | None | — | — | JP | disclosed |
| JP-57179153-A | — | — | None | — | — | JP | disclosed |
| CN-117898288-A | Redox-responsive pesticide prodrug composite microcapsule and preparation method thereof | 上海师范大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-117886853-A | Preparation method of reactive flame retardant, product thereof and application of reactive flame retardant in cotton fibers | 盐城工学院 | 2024-04-16 | — | — | CN | disclosed |
| EP-0037729-A2 | Process for penicillin epimerization | ELI LILLY AND COMPANY (US) | 1981-10-14 | — | — | EP | disclosed |
| US-4293495-A | Symmetrical azetidinone aldehyde disulfides and process | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4293493-A | Azetidinone alcohol disulfides and process for cyclization | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4293493-A | Azetidinone alcohol disulfides and process for cyclization | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4293493-A | Azetidinone alcohol disulfides and process for cyclization | ELI LILLY AND COMPANY (US) | 1981-10-06 | — | — | US | disclosed |