SCHEMBL13599459

SCHEMBL13599459

C/N=N/c1c(S(=O)(=O)[Mo])cc2c(/N=N/c3ccccc3)c(NCS(C)(=O)=O)ccc2c1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.38
EP300 Q09472 1/20 0.38
PRMT6 Q96LA8 1/20 0.38
PRMT1 Q99873 1/20 0.38
PHLPP2 Q6ZVD8 2/20 0.35
ENPP2 Q13822 3/20 0.35
CYP1A2 P05177 1/20 0.33
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
MPL P40238 1/20 0.31
MAPT P10636 2/20 0.31
MAPK1 P28482 2/20 0.31
GAA P10253 1/20 0.31
SUMO2 P61956 1/20 0.30
SUMO1 P63165 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP2 Q9HC62 1/20 0.30
SENP1 Q9P0U3 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12052488 0.96 PRMT3 (0.40) PRMT3EP300PRMT6PRMT1PHLPP2
SCHEMBL12052482 0.92
SCHEMBL13340401 0.83 PRMT3 (0.44) PRMT3EP300PRMT6PRMT1PHLPP2
SCHEMBL12052475 0.79 MPL (0.32) CA2CA3MPL
SCHEMBL14362723 0.76 PRMT3 (0.40) PRMT3EP300PRMT6PRMT1PHLPP2
SCHEMBL13340389 0.70
SCHEMBL13340418 0.69 PRMT3 (0.51) PRMT3EP300PRMT6PRMT1PHLPP2
SCHEMBL12052456 0.69 MPL (0.31) MPL
SCHEMBL12052478 0.68 MPL (0.42) PRMT3EP300PRMT6PRMT1PHLPP2
SCHEMBL14445775 0.67 PRMT3 (0.49) PRMT3EP300PRMT6PRMT1PHLPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7637964-B2 Dye mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO. (DE) 2009-12-29 US disclosed
US-20080274287-A1 Dye Mixtures Of Fiber-Reactive Azo Dyes, Their Preparation And Their Use DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-11-06 US disclosed
US-7429279-B2 Dye mixtures of fiber-reactive AZO dyes, their preparation and their use DYSTAR TEXTILFARBEN GMBH + CO. DEUTSCHLAND KG (DE) 2008-09-30 US disclosed