Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.57 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398165 | 0.90 | KMT2A (1.00) | KMT2ANAPRTLMNAP4HTML3MBTL1 | |
| SCHEMBL29373829 | 0.90 | KMT2A (1.00) | KMT2ANAPRTLMNAP4HTML3MBTL1 | |
| SCHEMBL28005707 | 0.88 | KMT2A (0.96) | KMT2ANAPRTLMNAP4HTML3MBTL1 | |
| SCHEMBL28015961 | 0.88 | KMT2A (0.96) | KMT2ANAPRTLMNAP4HTML3MBTL1 | |
| SCHEMBL29571462 | 0.85 | KMT2A (0.75) | KMT2ANAPRTLMNAP4HTML3MBTL1 | |
| SCHEMBL2485773 | 0.85 | KMT2A (0.75) | KMT2ANAPRTLMNAP4HTML3MBTL1 | |
| SCHEMBL507907 | 0.83 | KMT2A (0.72) | KMT2ANAPRTLMNAP4HTML3MBTL1 | |
| SCHEMBL743166 | 0.83 | KMT2A (0.72) | KMT2ANAPRTLMNAP4HTML3MBTL1 | |
| SCHEMBL8866141 | 0.83 | KMT2A (0.72) | KMT2ANAPRTLMNAP4HTML3MBTL1 | |
| SCHEMBL1156133 | 0.83 | KMT2A (0.72) | KMT2ANAPRTLMNAP4HTML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638531-B2 | Phenoxypiperidines and analogs thereof useful as histamine H3 antagonists | SCHERING CORPORATION (US) | 2009-12-29 | — | — | US | disclosed |
| US-7638531-B2 | Phenoxypiperidines and analogs thereof useful as histamine H3 antagonists | SCHERING CORPORATION (US) | 2009-12-29 | — | — | US | disclosed |
| US-20070167435-A1 | Phenoxypiperidines and analogs thereof useful as histamine H3 antagonists | SCHERING CORPORATION | 2007-07-19 | — | — | US | disclosed |
| US-20070167435-A1 | Phenoxypiperidines and analogs thereof useful as histamine H3 antagonists | SCHERING CORPORATION | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167435-A1 | Phenoxypiperidines and analogs thereof useful as histamine H3 antagonists | HRH4, HRH3, HRH2 | KMT2A 1324/4885NAPRT 3026/4885LMNA 4131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.