Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29571462 | 1.00 | KMT2A (0.75) | KMT2AHSD17B14CES2CES1MAPT | |
| SCHEMBL398165 | 0.86 | KMT2A (1.00) | KMT2AHSD17B14CES2CES1MAPT | |
| SCHEMBL29373829 | 0.86 | KMT2A (1.00) | KMT2AHSD17B14CES2CES1MAPT | |
| SCHEMBL13600090 | 0.85 | KMT2A (0.81) | KMT2AHSD17B14CES2CES1MAPT | |
| SCHEMBL28015961 | 0.84 | KMT2A (0.96) | KMT2AHSD17B14CES2CES1MAPT | |
| Phenol SCHEMBL17644331 | 0.84 | KMT2A (0.68) | KMT2AHSD17B14CES2CES1MAPT | |
| SCHEMBL28005707 | 0.84 | KMT2A (0.96) | KMT2AHSD17B14CES2CES1MAPT | |
| SCHEMBL743166 | 0.83 | KMT2A (0.72) | KMT2AHSD17B14CES2CES1MAPT | |
| SCHEMBL3830943 | 0.83 | KMT2A (0.72) | KMT2AHSD17B14CES2CES1RAB9A | |
| SCHEMBL507907 | 0.83 | KMT2A (0.72) | KMT2AHSD17B14CES2CES1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436946-A | Impurity in sodium picosulfate intermediate and preparation method thereof | 海南鑫开源医药科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| US-9496507-B2 | Emitting compound and organic light emitting diode device using the same | LG DISPLAY CO., LTD. (KR) | 2016-11-15 | — | — | US | disclosed |
| US-9496507-B2 | Emitting compound and organic light emitting diode device using the same | LG DISPLAY CO., LTD. (KR) | 2016-11-15 | — | — | US | disclosed |
| CN-103288717-B | Main chain is containing pyridine ring aromatics bisphenol type Terminal Acetylenes propyl ether resin and preparation method thereof | BEIHANG UNIVERSITY (CN) | 2015-08-12 | — | — | CN | disclosed |
| US-20140138657-A1 | EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE USING THE SAME | LG DISPLAY CO., LTD. (KR) | 2014-05-22 | — | — | US | disclosed |
| US-20140138657-A1 | EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE USING THE SAME | LG DISPLAY CO., LTD. (KR) | 2014-05-22 | — | — | US | disclosed |
| US-8637500-B2 | Aminopyridine and carboxypyridine compounds as phosphodiesterase 10 inhibitors | AMGEN INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-8637500-B2 | Aminopyridine and carboxypyridine compounds as phosphodiesterase 10 inhibitors | AMGEN INC. (US) | 2014-01-28 | — | — | US | disclosed |
| US-8637500-B2 | Aminopyridine and carboxypyridine compounds as phosphodiesterase 10 inhibitors | AMGEN INC. (US) | 2014-01-28 | — | — | US | disclosed |
| EP-2376455-B1 | AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS | AMGEN INC (US) | 2012-11-14 | — | — | EP | disclosed |
| EP-2376455-B1 | AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS | AMGEN INC (US) | 2012-11-14 | — | — | EP | disclosed |
| EP-2376455-A1 | AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS | Amgen Inc. (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010077992-A1 | AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS | AMGEN INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2010077992-A1 | AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS | AMGEN INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| US-20100160280-A1 | AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS | AMGEN INC. (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100160280-A1 | AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS | AMGEN INC. (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100160280-A1 | AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS | AMGEN INC. (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160280-A1 | AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS | PDE4A, PDE7A, PDE4D | KMT2A 2462/4885HSD17B14 1691/4885CES2 548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.