Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.66 |
| ▸ | TSHR | P16473 | 8/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13600934 | 0.87 | LMNA (0.65) | LMNAKDM4ENPSR1MAPTL3MBTL1 | |
| SCHEMBL4496337 | 0.82 | SMN1; SMN2 (0.63) | LMNAKDM4EMAPTALDH1A1TSHR | |
| SCHEMBL29709840 | 0.79 | KDM4E (0.74) | LMNAKDM4ENPSR1MAPTL3MBTL1 | |
| SCHEMBL18703057 | 0.79 | KDM4E (0.74) | LMNAKDM4ENPSR1MAPTL3MBTL1 | |
| SCHEMBL5567052 | 0.75 | LMNA (0.64) | LMNAKDM4ENPSR1MAPTL3MBTL1 | |
| SCHEMBL719242 | 0.75 | KDM4E (0.78) | LMNAKDM4ENPSR1MAPTL3MBTL1 | |
| SCHEMBL4503406 | 0.74 | KDM4E (0.67) | LMNAKDM4ENPSR1MAPTL3MBTL1 | |
| SCHEMBL13600918 | 0.74 | LMNA (0.62) | LMNAKDM4ENPSR1MAPTL3MBTL1 | |
| SCHEMBL20866638 | 0.74 | NPSR1 (0.64) | LMNAKDM4ENPSR1MAPTL3MBTL1 | |
| SCHEMBL4775716 | 0.74 | KDM4E (0.71) | LMNAKDM4ENPSR1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |